General Information |
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Product |
Angiopoietin-like 4 Positive Control |
Description |
Western Blot Positive Control Angiopoietin-related protein 4 |
Verified Applications |
WB |
Immunogen |
Purfied protein. |
Accession # |
NCBI: NP_065606.2 |
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Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
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Western Blot |
1:2,500-1:5,000 |
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Uniprot # |
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Overview |
Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation. |
Molecular Function |
enzyme inhibitor activity identical protein binding |
Subcellular Location |
Secreted |
Expression |
Predominantly expressed in adipose tissue and is strongly up-regulated by fasting in white adipose tissue and liver. |
Structure |
Coiled coil, Signal |
Alternative Nomenclature |
Angiopoietin like 4 antibody Angiopoietin-like protein 4 antibody ANGPT L2 antibody ANGPT L4 antibody Angptl4 antibody ARP4 antibody Fasting induced adipose factor antibody FIAF antibody HARP antibody Hepatic angiopoietin related protein antibody Hepatic fibrinogen/angiopoietin-related protein antibody HFARP antibody NL2 antibody Peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin related protein antibody PGAR antibody pp1158 antibody PPARG angiopoietin related protein antibody PSEC0166 antibody TGQTL antibody UNQ171 antibody Weakly similar to angiopoietin 1 [H.sapiens] antibody |
Protein information supplied by UniProt.
Product | Note | Status | Price | |
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ANGPTL4-101AP | |||
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ANGPTL4-BIOTIN | |||
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ANGPTL4-FITC | |||
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P-ANGPTL4 | |||
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