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General Information
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Product
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Sodium / Hydrogen Exchanger 3 Antibody Affinity Purified
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Description
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Affinity Purified Sodium/Hydrogen Exchanger 3 isoform 1 Antibody
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 790-835 on Slc9A3 protein.
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Accession #
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NCBI: NP_004165.2
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.68 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Western Blot
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1:500
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Protein
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Uniprot #
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P48764
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Overview
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Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
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Molecular Function
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PDZ domain binding; Sodium:proton antiporter activity
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Subcellular Location
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Apical cell membrane; Multi-pass membrane protein
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Structure
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Binds SLC9A3R1 and SLC9A3R2. Interacts with CHP1, CHP2 and SHANK2. Interacts with PDZK1 (via C-terminal PDZ domain) (By similarity). Interacts with PDZD3 and interactions decrease in response to elevated calcium ion levels.
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Alternative Nomenclature
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MGC126718 antibody
MGC126720 antibody
NHE3 antibody
SLC9A 3 antibody
Sodium/hydrogen exchanger 3 antibody
Solute carrier family 9 member 3 antibody
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Sodium / Hydrogen Exchanger 3 Antibody FITC
Sodium / Hydrogen Exchanger 3 Antibody BIOTIN
Sodium / Hydrogen Exchanger 3 Blocking Peptide
Sodium / Hydrogen Exchanger 3 Antibody Positve Control
