General Information
Product
C6orf150 Antibody BIOTIN-Conjugated
Description
BIOTIN-Conjugated Cyclic GMP-AMP synthase Antibody C-epitope
Verified Applications
ELISA, WB
Host
Rabbit
Species Cross Reactivity
Human
Immunogen
Synthetic peptide taken within amino acid regions 400-450 on human cGAS protein.
Accession #
NCBI: NP_612450
Physical Properties
Quantity
100 µg
Volume
200 µl
Concentration
0.60 µg/µl in antibody stabilization buffer
Form
BIOTIN-Conjugated
Clonality
Polyclonal
Determinant
C-epitope
Storage
-20⁰C for long term storage
Application Protocol
DB
1:10,000
ELISA
Western Blot
1:500
Protein
Uniprot #
Q8N884
Overview
Catalyzes the formation of cyclic GMP-AMP from ATP and GTP. Has antiviral activity through acting as a cystolic DNA senser.
Molecular Function
Nucleotidyltransferase; ATP binding; DNA binding
Subcellular Location
Cytoplasm; Cytosol
Expression
Is expressed in the monocytic cell line THP1 by type 1 Interferons
Structure
Monomer when in absence of DNA. Homodimer when bound to DNA.
Alternative Nomenclature
C6orf150 antibody
cGAMP synthase antibody
cGAS antibody
Chromosome 6 open reading frame 150 antibody
Cyclic GMP-AMP synthase antibody
h-cGAS antibody
Hypothetical protein LOC115004 antibody
Mab 21 domain containing 1 antibody
MB21D1 antibody
protein MB21D1 antibody
Uncharacterized protein C6orf150 antibody
Protein information supplied by UniProt
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