General Information
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Product
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Pan PDE3B Antibody BIOTIN-Conjugated
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Description
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BIOTIN-Conjugated cGMP-inhibited 3',5'-cyclic phosphodiesterase B Antibody
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Verified Applications
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CM, ELISA, ICC, IHC, IP, WB
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Host
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Goat
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Species Cross Reactivity
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Chicken, Human, Monkey, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 1060-1110 on human PDE3B protein.
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Specificity |
This antibody does not cross react with PDE4A variants nor with any other PDE famly members. This antibody will recognize PDE3B variants. |
Accession #
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Gen Bank: BAA09306
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55 µg/µl in antibody stabilization buffer
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Form
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BIOTIN-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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Confocal Microscopy
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1:500
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DB
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1:10,000
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ELISA
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1:10,000
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Immunocytochemistry
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1:500
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Immunofluorescence
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1:500
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Immunohistochemistry
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1:500
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Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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Q13370
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Overview
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Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3.
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Molecular Function
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Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding
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Subcellular Location
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Membrane; Multipass membrane protein
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Expression
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Abundant in adipose tissues.
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Structure
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Interacts with PIK3CG. Interacts with RAPGEF3 and PIK3R6 (By similarity).
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Alternative Nomenclature
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5''-cyclic phosphodiesterase B antibody
adipocyte cAMP phosphodiesterase cGMP inhibited antibody
AI847709 antibody
cAMP Phosphodiesterase, adipocyte, cGMP-inhibited antibody
CGIP1 antibody
CGIPDE B antibody
cGMP inhibited 3 5 cyclic phosphodiesterase B antibody
CGMP inhibited cAMP phophodiesterase antibody
cGMP-inhibited 3'' antibody
Cyclic GMP-inhibited phosphodiesterase B antibody
Cyclic nucleotide phosphodiesterase antibody
HcGIP1 antibody
Phosphodiesterase 3B cGMP inhibited antibody
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