General Information

Product

PAX4 Antibody

Description

Affinity Purified Paired Box Protein Pax-4 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse

Immunogen

Synthetic peptide taken within amino acid region 250-300, corresponding to unique amino acid sequence on PAX4 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.92-1.25 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

O43316

Overview

Functions in the differentiation of pancreatic islet beta cells, and is a transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters.

Molecular Function

Developmental protein, Repressor, DNA binding

Subcellular Location

Nucleus

Alternative Nomenclature

KPD antibody

MGC129960 antibody

MODY9 antibody

Paired box 4 antibody

paired box homeotic gene 4 antibody

Paired domain gene 4 antibody

Pax4 antibody

General Information

Product

LAMP2 Antibody

Description

Affinity Purified Lysosome-associated membrane glycoprotein 2 Antibody

Verified Applications

DB, ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse

Predicted: Rat

Immunogen

Synthetic peptide taken within amino acid region 260-310 on human lysosomal membrane glycoprotein-2.

Accession #

GenBank: AAB41647.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68-0.70 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P13473

Overview

Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion

Molecular Function

enzyme binding

Subcellular Location

Cell membrane, Endosome, Lysosome, Membrane

Expression

LAMP-2A is highly expressed in placenta, lung and liver, less in kidney and pancreas, low in brain and skeletal muscle.LAMP-2B is highly expressed in skeletal muscle, less in brain, placenta, lung, kidney and pancreas, very low in liver.

Structure

Belongs to the LAMP family

Alternative Nomenclature

CD107 antigen-like family member B antibody

CD107b antibody

LAMP 2 antibody

LAMP 2C antibody

LAMPB antibody

LGP110 antibody

Lysosome associated membrane protein 2 antibody

MAC3 antibody

General Information

Product

Pax2 Antibody

Description

Affinity Purified Paired box protein Pax-2 Antibody Multi-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50, 255-305, and 310-360 on human PAX2 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75-0.95 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Multi-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q02962

Overview

Probable transcription factor that may have a role in kidney cell differentiation. Has a critical role in the development of the urogenital tract, the eyes, and the CNS.

Molecular Function

Developmental protein, core promoter proximal region sequence-specific DNA binding, DNA binding

Subcellular Location

Nucleus

Expression

Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system.

Structure

Mainly in fetal kidney and juvenile nephrogenic rests.

Alternative Nomenclature

Paired box 2 antibody

Paired box gene 2 antibody

paired box protein 2 antibody

Paired box protein Pax 2 antibody

Pax 2 antibody

General Information

Product

Phospho-ErbB 2 Antibody

Description

Affinity Purified Receptor tyrosine-protein kinase erB-2 (HER2) Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Predicted: Human

Immunogen

Phoshporylated synthetic peptide taken within amino acid region 1100-1150 on human HER-2 protein

Accession #

GenBank:  AAA75493.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P04626

Overview

Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs).

Molecular Function

Activator, Kinase, Receptor, Transferase, Tyrosine-protein kinase

Subcellular Location

Isoform 1: Cell membrane; Single-pass type I membrane protein, Cytoplasm>perinuclear region, Nucleus. Isoform 2: Cytoplasm, Nucleus. Isoform 3: Cytoplasm, Nucleus.

Expression

Expressed in a variety of tumor tissues including primary breast tumors and tumors from small bowel, esophagus, kidney and mouth.

Structure

Homodimer. Heterodimer with EGFR, ERBB3 and ERBB4. Part of a complex with EGFR and either PIK3C2A or PIK3C2B. May interact with PIK3C2B when phosphorylated on Tyr-1196. Interacts with PRKCABP and PLXNB1. Interacts (when phosphorylated on Tyr-1248) with MEMO1. Interacts with MUC1; the interaction is enhanced by heregulin (HRG).

Alternative Nomenclature

Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog antibody

c erb B2/neu protein antibody

CD340 antibody

CerbB2 antibody

Erb B2 antibody

Erythroblastosis Virus antibody

HER 2/neu antibody

Herstatin antibody

Metastatic lymph node gene 19 protein antibody

MLN19 antibody

NEU antibody

Neuro Glioblastoma Derived Oncogene Homolog antibody

NGL antibody

p185 ErbB2 antibody

Receptor Protein Tyrosine Kinase ErbB2 Precursor antibody

TKR1 antibody

Tyrosine kinase-type cell surface receptor HER2 antibody

v erb b2 erythroblastic leukemia viral oncogene homolog 2 neuro/glioblastoma derived oncogene homolog (avian) antibody

verbb2 antibody

General Information

Product

Phospholipase A2 IIA Antibody Affinity Purified

Description

Affinity Purified Phospholipase A2, membrane associated Antibody

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 50-150 on human Phospholipase A2 membrane associated protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P14555

Overview

regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.

Molecular Function

Hydrolase

Subcellular Location

Membrane

Expression

Small intestine,heart,liver,lymph node,placenta & prostate.

Structure

Belongs to the phospholipase A2 family.

Alternative Nomenclature

EC 3.1.1.4 antibody

GIIC sPLA2 antibody

Group IIA phospholipase A2 antibody

membrane associated antibody

MOM1 antibody

Non pancreatic secretory phospholipase A2 antibody

NPSPLA2 antibody

Phosphatidylcholine 2-acylhydrolase 2A antibody

Phospholipase A2 antibody

PLA2 antibody

PLA2B antibody

PLA2G2A antibody

PLA2L antibody

PLA2S antibody

PLAS1 antibody

RASF A antibody

sPLA2 antibody

General Information

Product

CXCR1 Antibody Affinity Purified

Description

Affinity Purified Chemokine (C-X-C motif) receptor 1 Antibody

Verified Applications

ELISA, IP, WB

Host

Goat

Species Cross Reactivity

Mouse

Immunogen

Synthetic peptide corresponding to unique amino acid sequences on mouse CXCR1 protein.

Accession #

NCBI:  NM_178241.4

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

.50-1.2 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:250

Western Blot

1:500

Protein

Uniprot #

Q810W6

Overview

Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.

Molecular Function

Chemotaxis

Subcellular Location

Cell membrane; Multi-pass membrane protein

Structure

Belongs to the G-protein coupled receptor 1 family

Alternative Nomenclature

C C antibody

C C CKR 1 antibody

C-X-C chemokine receptor type 1 antibody

CCCKR1 antibody

CD 181 antibody

CD128 antibody

CKR 1 antibody

CMKAR1 antibody

CXC-R1 antibody

High affinity interleukin-8 receptor A antibody

IL 8 receptor type 1 antibody

IL 8R A antibody

General Information

Product

Phospho-Histone H3 Antibody (S10)

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Rat

Immunogen

Phosphorylated synthetic peptide taken within amino acid region 1-50 on HH3 protein.

Accession #

GenBank: CAA58540.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P68431

Overview

Core component of nucleosome.Play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

Molecular Function

DNA-binding

Subcellular Location

Nucleus; Chromosome

Expression

During Sphase, then expression decreases as cell division slows down during the process of differentiation.

Structure

Belongs to histone H3 family

Alternative Nomenclature

H3.3B antibody

H3F3A antibody

H3 histone antibody

H3 histone family member E pseudogene antibody

HIST3H3 antibody

Histone H3 3 pseudogene antibody

PP781 antibody

General Information

Product

C1orf146 Antibody

Description

Affinity Purified Chromosome 1 open reading frame 146 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 100-180 on human C1orf146 protein.

Accession #

NCBI:  NP_001012425

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68-0.70 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q5VVC0

Overview

Uncharacterized protein C1orf146

Alternative Nomenclature

C1orf146 antibody

CA146_HUMAN antibody

Chromosome 1 open reading frame 146 antibody

RP11-163M2.4 antibody

Uncharacterized protein C1orf146 antibody

General Information

Product

PNPLA3 Antibody

Description

Affinity Purified Patatin-like phospholipase domain-containing protein 3 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 150-200 on human Patatin-like phospholipase domain-containing protein 3.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q9NST1

Overview

Multifunctional enzyme which has both triacylglycerol lipase and acylglycerol O-acyltransferase activities.

Molecular Function

Phospholipase A2 Activity; Lipid degradation and metabolism; Acyltransferase; Hydrolase; Transferase

Subcellular Location

Membrane; Single-pass type II membrane protein

Expression

By changes in energy balance: down-regulated following very low-calorie diet, whereas refeeding elevates the mRNA level.

Structure

Contains 1 patatin domain

Alternative Nomenclature

Acylglycerol O acyltransferase antibody

Adiponutrin antibody

ADPN antibody

C22orf20 antibody

Calcium independent phospholipase A2 epsilon antibody

IPLA2-epsilon antibody

Patatin like phospholipase domain containing 3 antibody

patatin like phospholipase domain containing protein 3 antibody

phospholipase A2, calcium independent, epsilon antibody

General Information

Product

CCR1 Antibody

Description

Affinity Purified Chemokine (C-C motif) receptor 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on mouse CCR1 protein.

Accession #

GenBank: AAH64991

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P32246

Overview

C-C type chemokine receptor that binds MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3.  Also binds less efficiently to MIP-1-beta or MCP-1.  Subsequently transduces a signal by increasing the intracellular calcium ion level.  Also responsible for affecting stem cell proliferation.

Molecular Function

GPCR; Receptor; Transducer

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Hematopoietic cells

Structure

Belongs to G-protein coupled receptor 1 family.  Interacts with CREB3.

Alternative Nomenclature

C C chemokine receptor type 1 antibody

C C CKR 1 antibody

CCR-1 antibody

CD191 antibody

Chemokine C C motif receptor 1 antibody

CKR 1 antibody

CMKBR1 antibody

CMKR 1 antibody

HM145 antibody

LD78 receptor antibody

Macrophage inflammatory protein 1 alpha receptor antibody

RANTES R antibody

SCYAR1 antibody