General Information |
|
Product |
TLR7 Antibody FITC-Conjugated |
Description |
FITC-Conjugated Toll-like receptor 7 precursor Antibody |
Verified Applications |
ELISA, WB |
Host |
Rabbit |
Species Cross Reactivity |
Cat, Human, Mouse, Pig |
Immunogen |
Synthetic peptide taken within amino acid region 175-225 on human TLR7 protein. |
Accession # |
NCBI: NP_057646.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.65-0.72 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:20,000 |
ELISA |
1:20,000 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). |
Molecular Function |
Receptor, double-stranded RNA bindng, single-stranded RNA binding |
Subcellular Location |
Endoplasmic reticulum membrane; Single-pass type 1 membrane protein, Endosome, Lysosome, Cytoplasmic vesicle |
Expression |
Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells. |
Structure |
Interacts with MYD88 via their respective TIR domains. Interacts with UNC93B1 (By similarity). |
Alternative Nomenclature |
PRO285 antibody TLR 7 antibody Toll like receptor 7 antibody UNQ248 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
TLR-701AP | |||
|
P-TLR7 | |||
|
TLR7-BIOTIN | |||
|
PC-TLR7 | |||
Display accessory details |
Select your currency:
(c) FabGennix International Inc.