Receptor for IL17A, IL17F and, in dimer with IL17RE, for IL17C. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.
Molecular Function
interleukin-17 receptor activity
Subcellular Location
Isoform 1: membrane, single-pass type I membrane protein; Isoform 2: secreted
Expression
Widely expressed.
Alternative Nomenclature
CTLA 8 antibody
Cytotoxic T lymphocyte associated serine esterase 8 antibody
IL-17A antibody
IL17 antibody
Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8) antibody