General Information |
|
Product |
ITK Antibody BIOTIN |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 550-600 on human ITK protein. |
Accession # |
GenBank: BAA02873.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.54-0.57 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunohistochemistry | 1:50-1:150 |
Immunoprecipitation | 1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells. |
Molecular Function |
ATP binding, metal ion binding, non-membrane spanning protein tyrosine kinase activity |
Subcellular Location |
Cytoplasm (Note: Localizes in vicinity of cell surface receptors in plasma membrane after receptor stimulation) |
Expression |
T-cell lines and natural killer cell lines. |
Alternative Nomenclature |
EMT antibody Homolog of mouse T cell itk/tsk antibody IL 2 inducible T cell kinase antibody Itk antibody Kinase EMT antibody LPFS1 antibody LYK antibody MGC126257 antibody MGC126258 antibody PSCTK 2 antibody T cell specific kinase antibody TSK antibody Tyrosine protein kinase antibody Tyrosine protein kinase ITK/TSK antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-ITK | |||
|
ITK-101AP | |||
|
ITK-FITC | |||
|
PC-ITK | |||
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