General Information |
|
Product |
NHERF-1 Antibody FITC |
Description |
FITC-Conjugated Na(+)/H(+) exchange regulatory cofactor NHE-RF1 Antibody |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide corresponding to amino acids within region 255-305 on human Na(+)/H(+) exchange regulatory cofactor NHE-RF1. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5-1.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
FITC-Conjugated |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Storage |
-20?C for long term storage |
|
|
ELISA |
1:50,000 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500-1:5,000 |
|
|
Uniprot # |
|
Overview |
Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli (By similarity). Involved in the regulation of phosphate reabsorption in the renal proximal tubules. Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatozoa. |
Molecular Function |
beta-2 adrenergic receptor binding beta-catenin binding chloride channel regulator activity dopamine receptor binding gamma-aminobutyric acid transmembrane transporter activity growth factor receptor binding myosin II binding PDZ domain binding pho |
Subcellular Location |
Plasma membrane, cytoplasm |
Expression |
Detected in liver, kidney, pancreas, prostate, spleen, small intestine and placenta, in particular in the syncytiotrophoblast. |
Alternative Nomenclature |
EBP 50 antibody Ezrin radixin moesin binding phosphoprotein 50 antibody Na(+)/H(+) exchange regulatory cofactor NHE RF antibody Na+/H+ exchange regulatory co factor antibody NHERF 1 antibody NHERF antibody NHRF1_HUMAN antibody NPHLOP2 antibody Regulatory cofactor of Na(+)/H(+) exchanger antibody Slc9a3r1 antibody Sodium hydrogen exchanger regulatory factor 1 antibody Solute carrier family 9 (sodium/hydrogen exchanger) member 3 regulator 1 antibody Solute carrier family 9 isoform 3 regulatory factor 1 antibody |
Protein information supplied by UniProt.
Product | Note | Status | Price | |
---|---|---|---|---|
|
NHERF1-101AP | |||
|
NHERF1-BIOTIN | |||
|
P-NHERF1 | |||
|
PC-NHERF1 | |||
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