General Information
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Product
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MAPK10 Peptide
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Description
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Antigenic Blocking Peptide Mitogen-activated protein kinase 10 Antibody
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 375-425 on human Mitogen-activated protein kinase 10.
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Immunohistochemistry |
1:50-1:100 |
Competition/Depletion assay
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1:500
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Protein
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Uniprot #
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P53779
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Overview
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Serine/threonine-protein kinase involved in various processes such as neuronal proliferation, differentiation, migration and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway.
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Molecular Function
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Kinase, Serine/threonine-protein kinase, Transferase
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Subcellular Location
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Cytoplasm, Membrane, Mitochondrion, Nucleus
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Expression
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Specific to a subset of neurons in the nervous system. Present in the hippocampus and areas, cerebellum, striatum, brain stem, and weakly in the spinal cord. Very weak expression in testis and kidney.
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Structure
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The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
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Alternative Nomenclature
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c Jun kinase 3 antibody
c-Jun N-terminal kinase 3 antibody
JNK3 alpha protein kinase antibody
JNK3 antibody
JNK3A antibody
MAP kinase 10 antibody
MAP kinase p49 3F12 antibody
MAPK 10 antibody
mitogen activated protein kinase 10 antibody
PRKM10 antibody
protein kinase mitogen activated 10 antibody
SAPK1b antibody
Stress activated protein kinase 1b antibody
stress activated protein kinase beta antibody
Stress activated protein kinase JNK3 antibody
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