Regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation.
Molecular Function
ATP Binding, ion channel binding, non-membrane spanning protein tyrosine kinase activity, protein tyrosine kinase activity, enzyme binding
Subcellular Location
Cell membrane, cytoplasm, cytoskeleton. (Note: Newly synthesized protein initially accumulates in the Golgi region and traffics to the plasma membrane through the exocytic pathway)
Expression
Expressed in the epithelial cells of renal proximal tubules and stomach as well as hematopoietic cells in the bone marrow and spleen in the fetal tissues. In adult, expressed in epithelial cells of the renal proximal tubules and present in keratinocytes in the basal epidermal layer of the epidermis.
Alternative Nomenclature
c Yes antibody
Cellular Yes 1 protein antibody
HsT441 antibody
P61 YES antibody
Proto oncogene tyrosine protein kinase YES antibody
Proto-oncogene c-Yes antibody
Tyrosine-protein kinase Yes antibody
v yes 1 Yamaguchi sarcoma viral oncogene homolog 1 antibody