General Information
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Product
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TSLP Antibody
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Description
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Affinity Purified Thymic Stromal LymphoPoietin Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human
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Immunogen
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Synthetic peptide taken within amino acid region 50-100 on human Thymic Stromal LymphoPoietin.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5-1.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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Affinity Purified
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Purification Method
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Immobilized antigen affinity chromatography
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Clonality
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Polyclonal
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Storage
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-20C for long term storage
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Application Protocol
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ELISA
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1:50,000
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Immunoprecipitation
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1:200
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Western Blot
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1:500-1:5,000
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Protein
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Uniprot #
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Q969D9
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Molecular Function
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cytokine activity
interleukin-7 receptor binding
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Subcellular Location
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Extracellular region or secreted
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Expression
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Isoform 1 is expressed in a number of tissues including heart, liver and prostate. Isoform 2 is the predominant form in keratinocytes of oral mucosa, skin and in salivary glands. It is secreted into saliva.
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Structure
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Interacts with a receptor composed of CRLF2 and IL7R. Binding of TSLP to CRLF2/TSLPR is a mechanistic prerequisite for recruitment of IL7R to the high-affinity ternary complex.
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Alternative Nomenclature
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Thymic stromal lymphopoietin antibody
Thymic stromal lymphopoietin protein TSLP antibody
Tslp antibody
TSLP protein antibody
TSLP_HUMAN antibody
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