General Information |
|
Product |
Phospho BTK Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated Phospho-specific Bruton's Tyrosine Kinase Antibody |
Verified Applications |
ELISA, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Monkey, Mouse, Pig, Rat |
Immunogen |
Synthetic peptide corresponding to Human BTK amino acids 544-561 (phopsho Y551).
Sequence RYV LDD EY(p)T SSV GSK FPV |
Specificity | This antibody does not cross react to any other cellular protein. |
Accession # |
NCBI: NP_000052.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.6 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Non-receptor tyrosine kinase invovled in B lymphocyte development. |
Molecular Function |
Kinase; Transferase; Tyrosine-protein Kinase |
Subcellular Location |
Cytoplasm; Cell Membrane; Peripheral membrane: Nucleus. In steady state BTK is predominantly cytosolic. |
Expression |
B-lymphocytes |
Structure |
PH domain mediates binding to inositol polyphosphate and phosphoinositides, leading to its targeting with plasma membrane. Extended in the BTK kinase family by a region designated Tec homology domain, which has roughly 80 residues preceding SH3 domain. |
Alternative Nomenclature |
Agammaglobulinaemia tyrosine kinase antibody AGMX 1 antibody AT antibody ATK antibody B cell progenitor kinase antibody BPK antibody Bruton tyrosine kinase antibody Btk antibody IMD1 antibody MGC126261 antibody MGC126262 antibody PSCTK 1 antibody Tyrosine protein kinase BTK antibody XLA antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-PBTK | |||
|
PBTK-140AP | |||
|
PBTK-FITC | |||
|
PC-PBTK | |||
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