FabGennix PDE4D Antibody has been used in 38 Publications
Applications: Confocal microscopy, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western blot
Reactivity: Bovine, Human, Mouse, and Rat
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Massimi, Mara, et al. "Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." Journal of Cellular Biochemistry (2016).
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PMID: 27859531 Applications: Western Blot Reactivity: Human |
Petersen, T. S., et al. "Distribution and function of 3', 5'-Cyclic-AMP phosphodiesterases in the human ovary." Molecular and cellular endocrinology (2015).
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PMID: 25578602 Applications: Immunohistochemistry Reactivity: Human |
Guo, Jiejie, et al. "Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice." Neuroscience 263 (2014).
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PMID: 24434771 Applications: Western Blot Reactivity: Mouse |
Dong, Cun-Jian, et al. "Presynaptic Inhibition by α2 Receptor/Adenylate Cyclase/PDE4 Complex at Retinal Rod Bipolar Synapse." The Journal of Neuroscience 34.28 (2014).
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PMID: 25009274 Applications: Immunohistochemistry Reactivity: Rat |
Zhai, Kui, et al. "Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms." Cellular signalling 26.5 (2014).
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PMID: 24463006 Applications: Western Blot Reactivity: Rat |
Salazar, Norma C et al. “GRK2 Blockade with βARKct Is Essential for Cardiac Β2-Adrenergic Receptor Signaling Towards Increased Contractility.” Cell Communication and Signaling : CCS 11 (2013).
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PMCID: 3846709 Applications: Immunoprecipitation, Western Blot Reactivity: Mouse |
Al-Tawashi, Azza, and Chris Gehring. “Phosphodiesterase Activity Is Regulated by CC2D1A That Is Implicated in Non-Syndromic Intellectual Disability.” Cell Communication and Signaling?: CCS 11 (2013).
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PMCID: 3704924 Applications: Immunocytochemistry, Western Blot Reactivity: Mouse |
Wang, Zhen-Zhen et al. “RNA Interference-Mediated Phosphodiesterase 4D Splice Variants Knock-down in the Prefrontal Cortex Produces Antidepressant-Like and Cognition-Enhancing Effects.” British Journal of Pharmacology 168.4 (2013).
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PMCID: 3631387 Applications: Western Blot Reactivity: Mouse |
Michalski, Joel, et al. "Attenuation of inhibitory prostaglandin E2 signaling in Human lung fibroblasts is mediated by phosphodiesterase 4." American journal of respiratory cell and molecular biology 47.6 (2012).
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PMID: 23043089 Applications: Western Blot Reactivity: Human |
Al-Tawashi, Azza et al. “Protein Implicated in Nonsyndromic Mental Retardation Regulates Protein Kinase A (PKA) Activity.” The Journal of Biological Chemistry 287.18 (2012). |
PMCID: 3340277 Applications: Immunohistochemistry, Western Blot Reactivity: Mouse |
Keravis, Thérèse et al. “Disease Progression in MRL/lpr Lupus-Prone Mice Is Reduced by NCS 613, a Specific Cyclic Nucleotide Phosphodiesterase Type 4 (PDE4) Inhibitor.” Ed. Pierre Bobé. PLoS ONE 7.1 (2012).
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PMCID: 3256138 Applications: Western Blot Reactivity: Mouse |
Schaal, Sandra Marie et al. “The Therapeutic Profile of Rolipram, PDE Target and Mechanism of Action as a Neuroprotectant Following Spinal Cord Injury.” Ed. Valentin Ceña. PLoS ONE 7.9 (2012).
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PMCID: 3446989 Applications: Immunohistochemistry, Western Blot Reactivity: Rat |
Haque, Mohammed Z., Paulo S. Caceres, and Pablo A. Ortiz. “β-Adrenergic Receptor Stimulation Increases Surface NKCC2 Expression in Rat Thick Ascending Limbs in a Process Inhibited by Phosphodiesterase 4.” American Journal of Physiology - Renal Physiology 303.9 (2012).
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PMCID: 3518189 Applications: Western Blot Reactivity: Human |
Yougbare, Issaka, et al. "NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on Human lung tissues." American Journal of Physiology-Lung Cellular and Molecular Physiology 301.4 (2011).
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PMID: 21784969 Applications: Immunocytochemistry, Western Blot Reactivity: Rat |
Abusnina, Abdurazzag, et al. "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." Cellular signalling 23.1 (2011).
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PMID: 20807569 Applications: Western Blot Reactivity: Human |
Adderley, Shaquria P. et al. “Identification of Cytosolic Phosphodiesterases in the Erythrocyte: A Possible Role for PDE5.” Medical Science Monitor: International Medical Journal of Experimental and Clinical Research 17.5 (2011).
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PMCID: 3366467 Applications: Western Blot Reactivity: Human |
Gregg, Christopher J., et al. "β2-adrenergic receptor-coupled phosphoinositide 3-kinase constrains cAMP-dependent increases in cardiac inotropy through phosphodiesterase 4 activation." Anesthesia & Analgesia 111.4 (2010).
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PMID: 20705779 Applications: Western Blot Reactivity: Mouse |
Wang, Jianjie, Susan Bingaman, and Virginia H. Huxley. “Intrinsic Sex-Specific Differences in Microvascular Endothelial Cell Phosphodiesterases.” American Journal of Physiology - Heart and Circulatory Physiology 298.4 (2010).
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PMCID: 2853420 Applications: Confocal microscopy, Immunofluorescence, Western Blot Reactivity: Rat |
Tahseldar-Roumieh, Rima et al. “PDEs1-5 Activity and Expression in Tissues of Cirrhotic Rats Reveal a Role for Aortic PDE3 in NO Desensitization.” International Journal of Experimental Pathology 90.6 (2009).
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PMCID: 2803251 Applications: Western Blot Reactivity: Rat |
Li, Yuting et al. “Regulation of Amygdalar PKA by β-Arrestin-2/phosphodiesterase-4 Complex Is Critical for Fear Conditioning.”Proceedings of the National Academy of Sciences of the United States of America 106.51 (2009).
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PMCID: 2799795 Applications: Immunoprecipitation, Western Blot Reactivity: Mouse |
Dostaler-Touchette, V., et al. "Cyclic adenosine monophosphate (cAMP)-specific phosphodiesterase is functional in bovine mammary gland." Journal of dairy science 92.8 (2009).
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PMID: 21653225 Applications: Immunocytochemistry Reactivity: Bovine |
Whitaker, Christopher M., and Nigel G. F. Cooper. “The Novel Distribution of Phosphodiesterase-4 Subtypes Within the Rat Retina.” Neuroscience 163.4 (2009). |
PMCID: 2774823 Applications: Confocal microscopy, Immunofluorescence, Immunohistochemistry, Western Blot Reactivity: Rat |
Nomura-Furuwatari, Chizumi, et al. "Expression profiles of phosphodiesterase 4D splicing variants in osteoblastic cells." Journal of bone and mineral metabolism 26.2 (2008).
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PMID: 18301971 Applications: Western Blot Reactivity: Mouse |
Zhang, Han-Ting, et al. "Anxiogenic-like behavioral phenotype of mice deficient in phosphodiesterase 4B (PDE4B)." Neuropsychopharmacology 33.7 (2008).
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PMID: 17700644 Applications: Western Blot Reactivity: Mouse |
Whitaker, Christopher M. et al. “Rolipram Attenuates Acute Oligodendrocyte Death in the Adult Rat Ventrolateral Funiculus Following a Contusive Cervical Spinal Cord Injury.” Neuroscience letters 438.2 (2008).
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PMCID: 2530896 Applications: Confocal microscopy, Immunofluorescence Reactivity: Rat |
Lin, Rui, et al. "Changes in β 2-adrenoceptor and other signaling proteins produced by chronic administration of ‘β-blockers’ in a murine asthma model." Pulmonary pharmacology & therapeutics 21.1 (2008).
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PMCID: 2775056 Applications: Western Blot Reactivity: Mouse |
Creighton, Judy, et al. "Spectrin-anchored phosphodiesterase 4D4 restricts cAMP from disrupting microtubules and inducing endothelial cell gap formation." Journal of cell science 121.1 (2008).
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PMID: 18073242 Applications: Immunoprecipitation, Western Blot Reactivity: Human |
Fujita, Masahiro, et al. "In vivo and in vitro measurement of brain phosphodiesterase 4 in Rats after antidepressant administration." Synapse 61.2 (2007).
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PMID: 17117418 Applications: Western Blot Reactivity: Rat |
Sachs, Benjamin D. et al. “P75 Neurotrophin Receptor Regulates Tissue Fibrosis through Inhibition of Plasminogen Activation via a PDE4/cAMP/PKA Pathway.” The Journal of Cell Biology 177.6 (2007).
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PMCID: 2064370 Applications: Coimmunoprecipitation, Western Blot Reactivity: Mouse |
Terrin, Anna et al. “PGE1 Stimulation of HEK293 Cells Generates Multiple Contiguous Domains with Different [cAMP]: Role of Compartmentalized Phosphodiesterases.” The Journal of Cell Biology 175.3 (2006).
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PMCID: 2064521 Applications: Confocal microscopy, Immunofluorescence Reactivity: Human |
Dlaboga, Daniel, Hassan Hajjhussein, and James M. O'Donnell. "Regulation of phosphodiesterase-4 (PDE4) expression in Mouse brain by repeated antidepressant treatment: comparison with rolipram." Brain research 1096.1 (2006).
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PMID: 16730340 Applications: Western Blot Reactivity: Mouse |
Baxendale, Rhona W., and Lynn R. Fraser. "Mammalian sperm phosphodiesterases and their involvement in receptor‐mediated cell signaling important for capacitation." Molecular reproduction and development 71.4 (2005).
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PMID: 15856425 Applications: Immunofluorescence, Western Blot Reactivity: Mouse |
Giorgi, Mauro, et al. "The induction of cyclic nucleotide phosphodiesterase 4 gene (PDE4D) impairs memory in a water maze task." Behavioural brain research 154.1 (2004).
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PMID: 15302115 Applications: Western Blot Reactivity: Rat |
Gallagher, Helen C., et al. "Valproate activates phosphodiesterase-mediated cAMP degradation: relevance to C6 glioma G1 phase progression." Neurotoxicology and teRatology 26.1 (2004).
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PMID: 15001216 Applications: Western Blot Reactivity: Human |
Wang, Daguang, et al. "Cloning and characterization of novel PDE4D isoforms PDE4D6 and PDE4D7." Cellular signalling 15.9 (2003).
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PMID: 12834813 Applications: Western Blot Reactivity: Human |
Valente, Eliane GA, et al. "L-arginine and phosphodiesterase (PDE) inhibitors counteract fibrosis in the Peyronie’s fibrotic plaque and related fibroblast cultures." Nitric Oxide 9.4 (2003).
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PMCID: 14996430 Applications: Immunohistochemistry, Western Blot Reactivity: Human, Rat |
Kapiloff, Michael S., Nicole Jackson, and Nathan Airhart. "mAKAP and the ryanodine receptor are part of a multi-component signaling complex on the cardiomyocyte nuclear envelope." Journal of Cell Science 114.17 (2001).
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PMID: 11590243 Applications: Immunohistochemistry, Immunoprecipitation, Western Blot Reactivity: Human, Rat |
Farooqui, Shakeel M., et al. "Surgically induced cryptorchidism-related degenerative changes in spermatogonia are associated with loss of cyclic adenosine monophosphate-dependent phosphodiesterases type 4 in abdominal testes of rats." Biology of reproduction 64.6 (2001).
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PMCID: 11369582 Applications: Confocal microscopy, Immunocytochemistry, Western Blot Reactivity: Rat |
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