General Information |
|
Product |
DNA polymerase eta Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated Chain B, Yeast DNA polymerase Eta Antibody |
Verified Applications |
ELISA, WB |
Host |
Rabbit |
Species Cross Reactivity |
|
Immunogen |
Synthetic peptide taken within amino acid region 200-300 on Chain A, Yeast DNA polymerase Eta. |
Accession # |
NCBI: 1JIH_A |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.70-0.98 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Western Blot |
1:500 |
|
|
Uniprot # |
Q04049 |
Overview |
DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. Efficiently incorporates nucleotides opposite to other UV or oxidative DNA damages like O(6)-methylguanine, 7,8-dihydro-8-oxoguanine, 2,6-diamino-4-hydroxy-5-formamidopyrimidine of 2'-deoxyguanosine (FaPydG), or p-benzoquinone DNA adducts. |
Molecular Function |
Damaged DNA binding, Metal ion binding, DNA-directed DNA polymerase activity |
Subcellular Location |
Nucleus |
Expression |
Induced by UV radiation and heat shock. The mRNA is stabilized during stationary phase. |
Structure |
Interacts with POL30. This interaction is essential for the polymerase eta function. |
Alternative Nomenclature |
DNA polymerase eta antibody FLJ16395 antibody FLJ21978 antibody POLH antibody polymerase DNA directed eta antibody RAD30 antibody RAD30 homolog A antibody Xeroderma pigmentosum variant type protein antibody XPV antibody |
Protein information supplied by UniProt
1.I would like to the suitability of immunoprecipitation experiments for RAD30 polymerase products: RAD30-101AP, RAD30-FITC, RAD30-Biotin, P-RAD30, PC-RAD30 RAD30 polymerase.
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-RAD30 | |||
|
RAD30-101AP | |||
|
RAD30-FITC | |||
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PC-RAD30 | |||
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