General Information
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Product
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Prostaglandin E2 receptor EP3 subtype Antibody Western Blot Positive Control
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Description
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Western Blot Positive Control Prostaglandin E2 Receptor subtype isoform 7
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Verified Applications
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WB
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Immunogen
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Purified Protein
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Accession #
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NCBI: NP_942010.1
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Physical Properties
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Quantity
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5 Applications
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Volume
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Inquire
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Form
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Western Blot Positive Control
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Storage
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-20⁰C for long term storage
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Application Protocol
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Western Blot
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1:500
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Protein
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Uniprot #
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P43115
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Overview
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Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems (By similarity).
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Molecular Function
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Prostaglandin E receptor activity, G-protein coupled receptor
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Subcellular Location
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Cell membrane; Multi-pass membrane
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Expression
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Expressed in small intestine, heart, pancreas, gastric fundic mucosa, mammary artery and pulmonary vessels.
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Structure
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Belongs to the G-protein coupled receptor 1 family.
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Alternative Nomenclature
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EP 2 antibody
Human prostaglandin E2 receptor antibody
PGE2 receptor EP2 subtype antibody
Prostaglandin E receptor 2 EP2 subtype antibody
PTGER2 antibody
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