General Information
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Product
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ILK Antibody FITC
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Description
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FITC-Conjugated Integrin-linked protein kinase Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 400-452 on human Integrin-linked protein kinase.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.66-0.87 µg/µl in antibody stabilization buffer
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunohistochemistry |
1:50-1:150 |
Immunoprecipitation |
1:200 |
Western Blot
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1:500
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Protein
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Uniprot #
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Q13418
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Overview
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Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway.
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Molecular Function
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ATP binding, protein kinase binding, protein serine/threonine kinase activity, signal transducer activity
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Subcellular Location
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Cell junction, cell membrane, peripheral membrane protein, cytoplasmic side, cell projection
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Expression
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Highly expressed in heart followed by skeletal muscle, pancreas and kidney. Weakly expressed in placenta, lung and liver.
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Alternative Nomenclature
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59 kDa serine/threonine protein kinase antibody
DKFZp686F1765 antibody
ILK 1 antibody
ILK 2 antibody
ILK antibody
Integrin linked kinase 2 antibody
Integrin-linked protein kinase antibody
p59 antibody
p59ILK antibody
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