Phospho-PDE11A Positive Control

General Information

Product

Phospho-PDE11A Positive Control

Description

Western Blot Positive Control Phosphorylated Cyclic Nucleotide Phosphodiesterase 11A

Verified Applications

WB

Accession #

NCBI:  NP_543169

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Protein

Uniprot #

Q9HCR9

Overview

Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively.

Molecular Function

Hydrolase, metal-ion binding, cGMP binding

Subcellular Location

Cytoplasm

Expression

Isoform 1 is present in prostate, pituitary, heart and liver. It is however not present in testis nor in penis, suggesting that weak inhibition by Tadalafil is not relevant (at protein level). Isoform 2 may be expressed in testis. Isoform 4 is expressed in adrenal cortex.

Alternative Nomenclature

5''-cyclic-AMP and -GMP phosphodiesterase 11A antibody

cAMP and cGMP cyclic nucleotide phosphodiesterase 11A antibody

cGMP phosphodiesterase 11A antibody

Cyclic nucleotide phosphodiesterase 11A1 antibody

Dual 3' 5' cyclic AMP and GMP phosphodiesterase 11A antibody

Dual 3'' antibody phosphodiesterase 11A antibody

FLJ23693 antibody

MGC133355 antibody

MGC133356 antibody

PDE 11A antibody

pde11 antibody

PDE11A antibody

PDE11A1 antibody

pde11a2 antibody

Phosphodiesterase 11A antibody

PPNAD2 antibody