PDE4A10 Antibody

Product no.: PD4A10-1001AP

Description

General Information
Product	PDE4A10 Antibody
Description	Affinity Purified Phosphodiesterase 4A10 Antibody N-epitope
Verified Applications	ELISA, IP, WB
Host	Rabbit
Species Cross Reactivity	Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 1-50 on PDE4A10 protein.
Accession #	GenBank: AAF14352
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.45-0.65 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	N-epitope
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunoprecipitation	1:150
Western Blot	1:500
Protein
Uniprot #	P27815
Overview	Hydrolyzes the second messenger cAMP which is a key regulator of many important physiological processes.
Molecular Function	cAMP
Subcellular Location	Isoform 1: perinuclear region, Isoform 2: ruffle membrane, Isoform 4: Peripheral membrane protein, Isoform 6: perinuclear region, Isoform 7: Membrane, Cytoplasm
Expression	Isoform 1 is widely expressed. Isoform 2 is abundant in liver, stomach, testis, thyroid and adrenal glands. It is also found in placenta, kidney, pancreas, ovary, uterus, skin, monocytes, mast cells, macrophages, as well as in bronchial smooth muscle. Iso
Structure	Belongs to cyclic nucleotide phosphodiesterase family. PDE4 subfamily
Alternative Nomenclature	5''-cyclic phosphodiesterase 4A10 antibody PDE46 antibody phosphodiesterase 4A10 cAMP specific antibody phosphodiesterase isozyme 4A10 antibody phosphodiesterase type 4A10 antibody

Protein information supplied by UniProt