General Information
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Product
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PDE4B2 Antibody
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Description
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Affinity Purified cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 2 Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse
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Immunogen
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Synthetic peptide taken within amino acid region 1-50 on human PDE4B2 protein.
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Specificity |
This antibody will detect only PDE4B2. It will not label other PDE family members. |
Accession #
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NCBI: NP_001032416.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Determinant |
N-epitope |
Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation
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1:200
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Western Blot
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1:750
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Protein
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Uniprot #
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Q07343
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Overview
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Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.
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Molecular Function
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Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding
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Expression
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Expressed in brain, heart, lung and skeletal muscle.
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Alternative Nomenclature
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5''-cyclic phosphodiesterase 4B antibody
cAMP-specific 3'' antibody
DPDE4 antibody
dunce-like phosphodiesterase E4 antibody
MGC126529 antibody
PDE 4B antibody
PDE IVB antibody
PDE32 antibody
PDE4B5 antibody
PDEIVB antibody
Phosphodiesterase-4B2 cAMP-specific antibody
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