General Information |
|
Product |
PACAP Antibody FITC |
Description |
FITC-Conjugated Pituitary adenylate cyclase-activating polypeptide Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 125-176 on human Pituitary adenylate cyclase-activating polypeptide protein. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5-1.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
FITC-Conjugated |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:50,000 |
Immunohistochemistry | 1:50-1:250 |
Immunoprecipitation |
1:200 |
Western Blot |
1:2,500-1:5,000 |
|
|
Uniprot # |
|
Overview |
Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells. |
Molecular Function |
neuropeptide hormone activity peptide hormone receptor binding pituitary adenylate cyclase activating polypeptide activity pituitary adenylate cyclase-activating polypeptide receptor binding receptor binding signal transducer activity, downstream of receptor |
Subcellular Location |
Secreted |
Expression |
Interacts with ADCYAP1R1 (via N-terminal extracellular domain). |
Structure |
Belongs to the glucagon family. |
Alternative Nomenclature |
adenylate cyclase activating polypeptide 1 (pituitary) antibody PACAP antibody PACAP-related peptide antibody Pituitary adenylate cyclase-activating polypeptide 27 antibody Pituitary adenylate cyclase-activating polypeptide 38 antibody Pituitary adenylate cyclase-activating polypeptide antibody prepro-PACAP antibody PRP-48 antibody |
Protein information supplied by UniProt.
Product | Note | Status | Price | |
---|---|---|---|---|
|
PACA-101AP | |||
|
PACA-BIOTIN | |||
|
P-PACA | |||
|
PC-PACA | |||
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