General Information |
|
Product |
DAPK2 Antibody BIOTIN |
Description |
BIOTIN-Conjugated Death-associated protein kinase 2 Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide take within amino acid region 300-350 on mouse Death-associated protein kinase 2 protein. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5-1.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
BIOTIN-Conjugated |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:50,000 |
Immunohistochemistry | 1:50-1:150 |
Immunoprecipitation |
1:200 |
Western Blot |
1:2,500-1:5,000 |
|
|
Uniprot # |
|
Overview |
Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Capable of regulating both type I apoptotic and type II autophagic cell death signals. |
Molecular Function |
ATP binding calmodulin binding identical protein binding protein serine/threonine kinase activity |
Subcellular Location |
Cytoplasm autophagosome lumen |
Expression |
Expressed in peritubular interstitial cells of the renal cortex (PubMed:24906443). Isoform 1 is found in the adult brain while isoform 2 is expressed in brains of embryos and young mice (at protein level) (PubMed:21408167). |
Structure |
The autoinhibitory domain sterically blocks the substrate peptide-binding site by making both hydrophobic and electrostatic contacts with the kinase core. |
Alternative Nomenclature |
DAK2 antibody DAP kinase 2 antibody DAP kinase related protein 1 antibody DAP kinase related protein 1 beta isoform antibody DAP-kinase-related protein 1 antibody DAPK2 antibody Death associated protein kinase 2 antibody DRP 1 antibody |
Protein information supplied by UniProt.
Product | Note | Status | Price | |
---|---|---|---|---|
|
DAPK2-201AP | |||
|
PC-DAPK2 | |||
|
P-DAPK2 | |||
|
DAPK2-FITC | |||
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