General Information |
|
Product |
ITCH / AIP4 Antibody FITC-Conjugated |
Description |
FITC-Conjugated ITCH protein Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 250-300 human ITCH protein. |
Accession # |
GenBank: AAH11571.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.66 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunohistochemistry | 1:50-1:100 |
Immunoprecipitation | 1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It catalyzes 'Lys-29'-, 'Lys-48'- and 'Lys-63'-linked ubiquitin conjugation. It is involved in the control of inflammatory signaling pathways. |
Subcellular Location |
Cell membrane, cytoplasm, nucleus (Note: Associates with endocytic vesicles. May be recruited to exosomes by NDFIP1) |
Expression |
Widely expressed |
Alternative Nomenclature |
AIF4 antibody AIP4 antibody Atrophin 1 interacting protein 4 antibody dJ468O1.1 antibody E3 ubiquitin-protein ligase Itchy homolog antibody EC 6.3.2 antibody Itch antibody Itchy E3 ubiquitin protein ligase antibody NAPP1 antibody NFE2 associated polypeptide 1 antibody Ubiquitin protein ligase ITCH antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
ITCH-101AP | |||
|
P-ITCH | |||
|
ITCH-BIOTIN | |||
|
PC-ITCH | |||
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