General Information |
|
Product |
Pan PDE8A Antibody FITC-Conjugated |
Description |
FITC-Conjugated Pan Phosphodiesterase 8A Antibody C-epitope |
Verified Applications |
CM, ELISA, ICC, IF, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Bovine, Human, Monkey, Mouse, Rat |
Immunogen |
Synthetic cyclic peptide from C terminus common to all PDE8A variants. |
Specificity | This antibody will label only PDE8A variants. This antibody will not cross react with other PDE family members. |
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|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.75 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Determinant |
C-epitope |
Storage |
-20⁰C for long term storage |
|
|
Confocal Microscopy |
1:250 |
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunocytochemistry |
1:250 |
Immunofluorescence |
1:250 |
Immunohistochemistry |
1:250 |
Immunoprecipitation |
1:250 |
Western Blot |
1:500-1:2,000 |
|
|
Overview |
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development. |
Molecular Function |
3',5'-cyclic-AMP phosphodiesterase activity, Hydrolase, Metal-binding |
Subcellular Location |
Cytosol |
Expression |
Expressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon. |
Structure |
Belongs to cyclic nucleotide phosphodiesterase family. PDE8B subfamily. Contains 1 PAC (Pas-associated C-terminal) domain. Contains 1 PAS (PER-ARNT-SIM) domain. |
Alternative Nomenclature |
5''-cyclic phosphodiesterase 8A antibody cAMP specific cyclic nucleotide phosphodiesterase 8A antibody FLJ16150 antibody High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8A antibody HsT19550 antibody PDE 8A antibody Phosphodiesterase 8A antibody Weakly similar to 3'5'-cyclic-nucleotide phosphodiesterase antibody |
Protein information supplied by UniProt
Fabgennix PDE8A Antibody has been used in 12 Publications |
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Immunohistochemistry; Human |
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Western Blot; Mouse |
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Western Blot; Human, Mouse |
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Western Blot; Mouse |
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Western Blot; Rat |
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Western Blot; Mouse |
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Western Blot; Rat |
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Western Blot; Human |
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Immunoprecipitation, Western Blot; Mouse |
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Western Blot; Bovine |
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Confocal Microscopy, Immunofluorescence, Western Blot; Human |
|
Immunoprecipitation; Mouse |
Publishing research using PD5A-101AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
---|---|---|---|---|
|
PD8A-121AP | |||
|
P-PD8A.c | |||
|
PD8A.c-BIOTIN | |||
|
PC-PD8A | |||
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(c) FabGennix International Inc.