General Information |
|
Product |
Aph 1b Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated Presenelin-stabiliziation factor-like Antibody |
Verified Applications |
ELISA, WB |
Host |
Rabbit |
Species Cross Reactivity |
C. elegans, Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 235-257 of Human Presenilin stabilizing protein. |
Specificity | APH1B-BIOTIN does not cross react to other components of gamma secretase complex nor with other proteins. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.6 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Subunit of gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and beta-amyloid precursor protein. |
Molecular Function |
Notch signaling pathway |
Subcellular Location |
Membrane; Multi-pass protein |
Expression |
Weakly expressed in leukocytes, lung, placenta, small intestine, liver, kidney, spleen, thymus, colon, skeletal muscle, heart, and brain. |
Structure |
Component of gamma-secretase complex. Interacts with PSEN1 and PSEN2. |
Alternative Nomenclature |
Anterior pharynx defective 1B like antibody Gamma secretase subunit APH 1B antibody Presenilin stabilisation factor like antibody PRO1328 antibody PSFL antibody TAAV 688 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-APH1B | |||
|
APH1B-101AP | |||
|
APH1B-FITC | |||
|
PC-APH1B | |||
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