General Information
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Product
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Phospho-CACNB2 Antibody
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Description
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Affinity Purified Voltage dependent L-type calcium channel subunit beta-2 Antibody
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Verified Applications
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Cell labeling, ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 600-655 on rat CACNB2 protein.
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Accession #
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NCBI: NP_446303
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.6 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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Dot Blot
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation |
1:200 |
Western Blot
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1:500
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Protein
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Uniprot #
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Q8VGC3
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Overview
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The beta subunit of voltage-dependent calcium channel which contributes to calcium channel function by increasing peak calcium current, shifting the voltage dependencies fo activation and inactivation, modulating G-protein inhibition and controllin the alpha-1 subunit membrane targeting.
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Molecular Function
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Calcium; Transport; Ion transport
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Subcellular Location
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Cell membrane; Sacrolemma; Peripheral membrane protein, cytoplasmic side
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Expression
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Heart and brain. Lower expression in lung.
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Structure
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L-type channel is composed of four subunits: alpha-1, alpha-2, beta and gamma.
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Alternative Nomenclature
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AW060387 antibody
Ca(V) beta 2 antibody
CAB2 antibody
CAVB2 antibody
Cavbeta2 antibody
Cchb2 antibody
Lambert Eaton Myasthenic syndrome antigen antibody
MYSB antibody
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