General Information |
|
Product |
ORP150 Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated Hypoxia up regulated 1 Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Monkey, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 950-999 on human Hypoxia up regulated 1. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:10,000 |
Immunohistochemistry | 1:50-1:100 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. |
Molecular Function |
ATP binding; chaperone binding |
Subcellular Location |
Endoplasmic reticulum lumen |
Expression |
Highly expressed in tissues that contain well-developed endoplasmic reticulum and synthesize large amounts of secretory proteins. Highly expressed in liver and pancreas and lower expression in brain and kidney. Also expressed in macrophages within aortic atherosclerotic plaques, and in breast cancers. |
Structure |
Part of a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX. Belongs to the heat shock protein 70 family. |
Alternative Nomenclature |
150 kDa oxygen regulated protein antibody 170 kDa glucose regulated protein antibody DKFZp686N08236 antibody FLJ94899 antibody FLJ97572 antibody glucose regulated protein 170 antibody Grp 170 antibody Grp170 antibody HSP 12A antibody HSP12A antibody Hyou1 antibody Hypoxia up regulated 1 antibody Orp 150 antibody Orp150 antibody oxygen regulated protein (150kD) antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
HYOU1-101AP | |||
|
P-HYOU1 | |||
|
HYOU1-FITC | |||
|
PC-HYOU1 | |||
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