General Information |
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Product |
Cell Surface Glycoprotein MUC18 Positive Control |
Description |
Western Blot Positive Control Cell Surface Glycoprotein MUC18 Antibody |
Verified Applications |
WB |
Immunogen |
Purified protein. |
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Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
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Western Blot |
1:2,500-1:5,000 |
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Uniprot # |
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Overview |
lays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. |
Subcellular Location |
Cell membrane; Single-pass type I membrane protein |
Expression |
Detected in lung, uterus and placenta (at protein level). Detected in heart, lung, kidney, adrenal gland, intestine, testis, skeletal muscle and aorta. Detected at low levels in adult brain, in particular in brain stem and spinal cord, but also in hippocampus, olfactory bulb and striatum (at protein level). |
Structure |
Immunoglobulin domain, Repeat, Signal, Transmembrane, Transmembrane helix |
Alternative Nomenclature |
A32 antigen antibody CD 146 antibody Cell surface glycoprotein MUC18 antibody Cell surface glycoprotein P1H12 antibody Gicerin antibody Mcam antibody Melanoma adhesion molecule antibody Melanoma associated antigen A32 antibody Melanoma associated antigen MUC18 antibody Melanoma associated glycoprotein MUC18 antibody MelCAM antibody MUC 18 antibody S endo 1 antibody S endo 1 endothelial associated antigen antibody |
Protein information supplied by UniProt.
Product | Note | Status | Price | |
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MUC18-101AP | |||
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MUC18-BIOTIN | |||
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MUC18-FITC | |||
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P-MUC18 | |||
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