General Information

Product

PNPLA3 Antibody

Description

Affinity Purified Patatin-like phospholipase domain-containing protein 3 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 150-200 on human Patatin-like phospholipase domain-containing protein 3.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q9NST1

Overview

Multifunctional enzyme which has both triacylglycerol lipase and acylglycerol O-acyltransferase activities.

Molecular Function

Phospholipase A2 Activity; Lipid degradation and metabolism; Acyltransferase; Hydrolase; Transferase

Subcellular Location

Membrane; Single-pass type II membrane protein

Expression

By changes in energy balance: down-regulated following very low-calorie diet, whereas refeeding elevates the mRNA level.

Structure

Contains 1 patatin domain

Alternative Nomenclature

Acylglycerol O acyltransferase antibody

Adiponutrin antibody

ADPN antibody

C22orf20 antibody

Calcium independent phospholipase A2 epsilon antibody

IPLA2-epsilon antibody

Patatin like phospholipase domain containing 3 antibody

patatin like phospholipase domain containing protein 3 antibody

phospholipase A2, calcium independent, epsilon antibody

General Information

Product

Adiponectin Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Pig

Immunogen

Synthetic peptide taken within amino acid region 150-243 on pig Adiponectin protein.

Accession #

GenBank: AY589691

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.65 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q69907

Overview

Involved in brown fat cell differentiation, responses to drugs, detection of oxidative stress glucose homeostasis and fatty acid oxidation.  Invovled in regulation of DNA biosynthetic processes.

Molecular Function

Hormone activity; receptor binding

Subcellular Location

Cell periphery; collagen trimer; extracellular space; cell surface; endoplasmic reticulum; perinuclear region of cytoplasm

Expression

Secreted

Alternative Nomenclature

30 kDa adipocyte complement related protein antibody

ACDC antibody

ACRP 30 antibody

Adipocyte antibody

Adipocyte C1q and collagen domain containing protein antibody

Adipocyte complement related 30 kDa protein antibody

adipocyte-specific secretory protein antibody

Adiponectin antibody

adiponectin, C1Q and collagen domain containing antibody

AdipoQ antibody

Adipose most abundant gene transcript 1 antibody

Adipose specific collagen like factor antibody

ADIPQTL1 antibody

ADPN antibody

APM 1 antibody

C1q and collagen domain-containing protein antibody

GBP 28 antibody

Gelatin binding protein antibody

Gelatin binding protein 28 antibody

General Information

Product

Fbx32 Antibody

Description

Affinity Purified Atrogin Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Rat, Mouse

Immunogen

Synthetic peptide taken within amino acid region 240-280 on Atr1 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q969P5

Overview

Substrate recognition component of a SCF E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Molecular Function

Ubl conjugation pathway

Subcellular Location

Cytoplasm; Nucleus

Expression

Cardiac and skeletal muscle

Structure

Contains 1 F-box domain

Alternative Nomenclature

Atrophy gene 1 antibody

F-box only protein 32 antibody

fbxo25 antibody

Muscle atrophy F-box protein antibody

General Information

Product

ANGPTL5 Antibody

Description

Affinity Purified Angiopoietin-related protein 5 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 340-388 on human ANGPTL5 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.66 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q86XS5

Overview

Growth factors specific for vascular endothelium.  Modulate angiogenesis and maintain vascular integrity.

Molecular Function

Secreted; extracellular region

Expression

Mainly expressed in adult heart

Structure

Contains 1 fibrinogen C-terminal domain

Alternative Nomenclature

Fibrinogen like antibody

General Information

Product

CCR5 Antibody

Description

Affinity Purified Chemokine receptor type 5 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human CCR5 protein.

Accession #

NCBI: AAB65720.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.70 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P51681

Overview

Receptor for several inflammatory C-C chemokines.  May play a role in control of granulocytic lineage proliferation or differentiation.

Molecular Function

actin binding; C-C chemokin binding; GPCR; Receptor; Transducer; Host-virus interaction

Subcellular Location

Cell membrane; Mulipass membrane protein.

Expression

Spleen, Thymus, myeloid cell line THP-1, promyeloblastic cell line KG-1a and on CD4+ and CD8+ T-cells.  Lesser expressed in peripheral blood leukocytes, small intestine and ovary and lung.

Structure

Interacts with PRAF2, HIV-1 surface protein gp120. Glycosylation on Ser-6 is required for binding with CCL4.

Alternative Nomenclature

AM4 7 antibody

CCCKR 5 antibody

CD 195 antibody

CHEMR13 antibody

HIV 1 Fusion Coreceptor antibody

IDDM22 antibody

MIP-1 alpha receptor antibody

General Information

Product

CD36 Antibody Affinity Purified

Description

Affinity Purified platelet glycoprotein 4 isoform 1 Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on human CD36 protein.

Accession #

NCBI:  NP_001120916.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P16671

Overview

Involved in binding to collagen, thrombospodin, anionic phospholipids and oxidized low density lipoprotein.  Serves to bind long chain fatty acids and  also may act as a cell adhesion molecule, or regulator of fatty acid transport.

Molecular Function

Lipoprotein particle binding; thrombospondin receptor activity; Receptor

Subcellular Location

Membrane; Multipass membrane protein

Structure

Interacts with THBS1 and THBS2, mediating THBS antiangiogenic activity.

Alternative Nomenclature

Adipocyte membrane protein antibody

thrombospondin receptor) antibody

cd36 antigen antibody

CHDS7 antibody

Cluster determinant 36 antibody

Collagen receptor, platelet antibody

FAT antibody

fatty acid translocase antibody

glycoprotein iiib antibody

GP IIIb antibody

gp4 antibody

gpiv antibody

leukocyte differentiation antigen cd36 antibody

PAS 4 protein antibody

platelet collagen receptor antibody

scarb3 antibody

Scavenger receptor class B member 3 antibody

thrombospondin receptor antibody

General Information

Product

Cofilin Antibody

Description

Affinity Purified Cofilin-1 Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 120-166 on human Cofilin protein.

Accession #

NCBI: BAA00589.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Dot blot

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P23528

Overview

Binds to F-actin and exhibits pH-sensitive depolymerizing activity.  Also regulates cytoskeleton dynamics.

Molecular Function

Actin-Binding

Subcellular Location

Cell membrane; Cell projection; Cytoplasm; Cytoskeleton; Membrane; Nucleus

Expression

Various tissues

Structure

Contains 1 ADF-H domain and belongs to actin-binding proteins ADF family

Alternative Nomenclature

18 kDa phosphoprotein antibody

CFL 1 antibody

epididymis secretory protein Li 15 antibody

HEL-S-15 antibody

non-muscle isoform antibody

p18 antibody

General Information

Product

CTGF Antibody

Description

Affinity Purified Connective Tissue Growth Factor Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 300-350 on human CTGF protein.

Accession #

GenBank: CAG46534.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.66 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:100

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q6FHL8

Overview

Involved in the regulation of cell growth

Molecular Function

Regulation of cell growth

Subcellular Location

Extracellular region

Expression

Testis, spleen, kidney, lung, heart, and brain (lowest level in testis and highest in lung).

Structure

Belongs to the CCN family.

Contains 1 CTCK (C-terminal cystine knot-like) domain.

Contains 1 IGFBP N-terminal domain.

Contains 1 TSP type-1 domain.

Contains 1 VWFC domain.

Alternative Nomenclature

CCN 2 antibody

Connective Tissue Growth Factor antibody

CTGF antibody

Hcs24 antibody

Hypertrophic chondrocyte specific protein 24 antibody

IBP-8 antibody

IGF-binding protein 8 antibody

Insulin like Growth Factor Binding Protein 8 antibody

MGC102839 antibody

NOV 2 antibody

General Information

Product

EDIL3 Antibody

Description

Affinity Purified EGF-like repeat and discoidin I-like domain-containg protein 3 isoform Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Cat, Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 30-60 on Del-1 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.69-0.70 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20°C for long term storage

Application Protocol

DB

1:20,000

ELISA

1:20,000

Western Blot

1:500

Protein

Uniprot #

O35474

Overview

Promotes endothelial cells through interaction with the alpha-v/beta-3 integrin receptor.  Inhibits formation of vascular-like structures.

Molecular Function

Calcium, Metal-binding

Subcellular Location

Secreted

Expression

Angioblasts and early endothelial cells

Structure

Contains 3 EGF-like domains; Contains 3 F5/8 type C domains

Alternative Nomenclature

DEL1 antibody

Developmentally regulated endothelial cell locus 1 protein antibody

EGF like repeat and discoidin I like domain containing protein 3 antibody

Integrin-binding protein DEL1 antibody

General Information

Product

EHD1 Antibody

Description

Affinity Purified EH domain-containing protein 1 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken wtihin amino acid region 515-565 on human EH-domain containing protein 1.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.58 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9H4M9

Overview

Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Plays a role in myoblast fusion. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth.

Molecular Function

Rab GTPase binding; ATP binding; calcium ion binding

Subcellular Location

Cell membrane, Endosome, Membrane

Expression

testis

Structure

Homooligomer, and heterooligomer with EHD2, EHD3 and EHD4, ATP-binding is required for heterooligomerization.

Alternative Nomenclature

CDABP0131 antibody

EH domain containing 1 antibody

FLJ42622 antibody

FLJ44618 antibody

H PAST antibody

PAST antibody

PAST1 antibody

Testilin antibody