General Information

Product

EHD4 Antibody

Description

Affinity Purified EH domain-containing protein 4 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse Rat

Immunogen

Synthetic peptide taken within amino acid region 420-450 on EH-domain containing 4 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9H223

Overview

Plays a role in early endosomal transport

Molecular Function

ATP binding;GTPase activity;nucleic acid binding;calcium ion binding;GTP binding

Subcellular Location

Cell membrane, Endosome, Membrane

Expression

Highly expressed in pancreas and heart.

Structure

Homooligomer, and heterooligomer with EHD1, EHD2 and EHD3

Alternative Nomenclature

EH domain containing 4 antibody

Hepatocellular carcinoma associated protein 10/11 antibody

HCA11 antibody

HGNC:3245 antibody

Ortholog of rat pincher antibody

PAST4 antibody

General Information

Product

SLC29A3 Antibody Affinity Purified

Description

Affinity Purified Equilibrative Nucleoside Transporter 3 isoform A Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-60 on ENT3 protein.

Accession #

NCBI: NP_060814.4

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9BZD2

Overview

Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter)

Molecular Function

nucleoside transmembrane transporter activity

Subcellular Location

Endosome, Lysosome, Membrane

Expression

Widely expressed in both adult and fetal tissues. Highest levels in placenta, uterus, ovary, spleen, lymph node and bone marrow. Lowest levels in brain and heart

Structure

Belongs to the SLC29A/ENT transporter (TC 2.A.57) family

Alternative Nomenclature

ENT3 antibody

Equilibrative nucleoside transporter 3 antibody

HCLAP antibody

hENT3 antibody

HJCD antibody

PHID antibody

SLC29A3 antibody

solute carrier family 29 (equilibrative nucleoside transporter), member 3 antibody

General Information

Product

FFAR3 Antibody

Description

Affinity Purified Free fatty acid receptor A3 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 270-320  on human FFAR3 protein.

Accession #

NCBI:  NP_005295.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.58-0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

O14843

Overview

G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins. Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation (PubMed:12711604). 

Molecular Function

G-protein coupled receptor activity; Lipid binding

Subcellular Location

Cell Membrane; Multi-Pass Membrane Protein

Expression

Highest level in adipose tissue, and lower expression across all tissues tested. Expressed in sympathetic ganglia.

Structure

Belongs to the G-protein coupled receptor 1 family.

Alternative Nomenclature

FFA3R antibody

Free fatty acid receptor 3 antibody

G protein coupled receptor 41 antibody

GPCR41 antibody

GPR41 antibody

gpr42 antibody

General Information

Product

GGCX Antibody 

Description

Affinity Purified Gamma-glutamic carboxylase Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 400-450 on human GGCX protein.

Accession #

GenBank: AAA91834.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DOT Blot

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P38435

Overview

Mediates the vitamin K-dependent carboxylation of glutatmate residues to calcium-binding gamma-carboxyglutamate residues with the concomitant converstion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.

Molecular Function

gamma-glutamyl carboxylase activity; Lyase

Subcellular Location

Endoplasmic Reticulum membrane; Multi-pass membrane protein

Expression

Monomer; may interact with CALU

Alternative Nomenclature

FLJ26629 antibody

Gamma glutamyl carboxylase antibody

Gamma-glutamyl carboxylase antibody

GC antibody

GGCX antibody

Peptidyl glutamate 4 carboxylase antibody

Peptidyl-glutamate 4-carboxylase antibody

Vitamin K dependent gamma carboxylase antibody

Vitamin K gamma glutamyl carboxylase antibody

Vitamin K-dependent gamma-carboxylase antibody

VKCFD 1 antibody

VKCFD1 antibody

VKGC_HUMAN antibody

General Information

Product

GIRK1 Antibody

Description

Affinity Purified G protein-activated inward rectifier potassium channel 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Accession #

NCBI: NP_113798

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.60-0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P63251

Overview

Potassium channel controlled by G-proteins.  Inward rectifier potassium channel characterized by greater tendency to allow potassium to flow into cell rather than out.  Plays crucial role in regulating heartbeat.

Molecular Function

Potassium

Subcellular Location

Membrane; Multi-pass membrane protein

Structure

Associated with GIRK2, GIRK3, GIRK4 to form a G-protein activated heteromultimer pore-forming unit.

Alternative Nomenclature

G protein activated inward rectifier potassium channel 1 antibody

GIRK-1 antibody

Inward rectifier K(+) channel Kir3.1 antibody

Kcnj3 antibody

KGA antibody

KGB1 antibody

Kir3.1 antibody

Potassium channel antibody

Potassium channel, inwardly rectifying subfamily J member 3 antibody

General Information

Product

GIRK4 Antibody Affinity Purified

Description

Affinity Purified G protein-activated inward rectifier potassium channel 4 Antibody

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 350-450 on human GIRK4 protein.

Accession #

NCBI: NP_000881

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.53-0.57 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:250

Protein

Uniprot #

P48544

Molecular Function

Potassium

Subcellular Location

Membrane; Multi-pass membrane protein

Structure

Belongs to inward rectifier-type potassium channel family

Alternative Nomenclature

Cardiac ATP sensitive potassium channel antibody

Cardiac inward rectifier antibody

CIR antibody

G protein activated inward rectifier potassium channel 4 antibody

GIRK-4 antibody

Heart KATP channel antibody

Inward rectifier K+ channel KIR3.4 antibody

IRK-4 antibody

KATP-1 antibody

KCNJ 5 antibody

KIR3.4 antibody

Potassium channel antibody

General Information

Product

Glucose Transporter GLUT10 Antibody 

Description

Affinity Purified Solute carrier family 2 (facilitated glucose transporter), member 10 Antibody

Verified Applications

ELISA, ICC/IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within C-terminal region, amino acids 500-536 of rat Glucose Transporter GLUT10 protein. Peptide was covalently modified and coupled to a carrier protein.

Accession #

NCBI:  EDL96452.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.54 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:100

DB

1:4,500

ELISA

1:4,500

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

UPI000155277B

Overview

Facilitative glucose transporter

Molecular Function

Sugar transport, Transport

Subcellular Location

Endomembranesystem; Multi-pass membrane protein; perinuclear region

Expression

Widely expressed; highest levels in liver and pancreas.

Structure

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Alternative Nomenclature

AA450473 antibody

facilitated glucose transporter member 10 antibody

Glucose transporter type 10 antibody

glut 10 antibody

MGC126706 antibody

SLC2A10 antibody

Solute carrier family 2 antibody

General Information

Product

HAND2 Antibody

Description

Affinity Purified heart- and neural crest derivatives-expressed protein 2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-100 on Human HAND2 protein.

Accession #

NCBI: NP_073187

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

.5-.6 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P61295

Overview

Essential for cardiac morphogenesis, particularly for he formation of the right ventricle and of the aortic arch arteries.

Molecular Function

DNA-Binding

Subcellular Location

Nucleus

Structure

Contains 1 basic helix-loop-helix domain

Alternative Nomenclature

AI225906 antibody

AI661148 antibody

autonomic nervous system and neural crest derivatives-expressed protein 2 antibody

Basic helix loop helix transcription factor HAND2 antibody

bHLHa26 antibody

Class A basic helix-loop-helix protein 26 antibody

Deciduum antibody

DHAND 2 antibody

Ehand 2 antibody

FLJ16260 antibody

heart antibody

Hed antibody

Highly similar to dHAND M musculus antibody

MGC125303 antibody

MGC125304 antibody

Th 2 antibody

Thing2 antibody

General Information

Product

HDAC4 Antibody

Description

Affinity Purified Histone deacetylase 4 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1,000-1,084 on human HDAC4 protein.

Accession #

GeneBank: AAH39904

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.63 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q86YH7

Overview

Responsible for deacetylation of lysine residues on the N-terminal part of the core histones.  Histone deacetylation gives a tag for epigenetic repression and plays and important role in transcriptional regulation, cell cycle progression and developmental events.

Molecular Function

Metal-binding; Zinc

Subcellular Location

Nucleus

Structure

Belongs to the histone deacetylase family. HD type 2 subfamily

Alternative Nomenclature

AHO3 antibody

BDMR antibody

EC 3.5.1.98 antibody

HA6116 antibody

HD 4 antibody

HDAC A antibody

Histone Deacetylase A antibody

KIAA0288 antibody

General Information

Product

Junctional Adhesion Molecule 1 Antibody

Description

Affinity Purified Junctional adhesion molecule A Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Monkey, Mouse, Panda, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-299 on human Junctional Adhesion Molecule A protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.52-0.63 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9Y624

Overview

Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3.  Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

Subcellular Location

Cell junction, cell membrane, single-pass type I membrane protein (Note: Localized at tight junctions of both epithelial and endothelial cells)

Alternative Nomenclature

9130004G24 antibody

AA638916 antibody

CD 321 antibody

ESTM33 antibody

F11 receptor antibody

F11R antibody

JAM 1 antibody

JAM A antibody

JCAM antibody

Junction adhesion molecule 1 antibody

KAT antibody

Ly106 antibody

PAM1 antibody

Platelet adhesion molecule 1 antibody

Platelet F11 receptor antibody

PRO301 antibody

UNQ264/PRO301 antibody