DNA PKcs Blocking Peptide

General Information

Product

DNA PKcs Blocking Peptide

Description

Antigenic Blocking Peptide DNA-dependent protein kinase catalytic subunit Antibody

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synthetic peptide taken within amino acid region 4000-4128 of human DNPK1 protein.

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20°C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

P78527

Overview

Receptor for netrin required for axon guidance; may trigger signaling for axon repulsion; acts as a dependence receptor required for apoptosis induction; tumor suppressor gene.

Molecular Function

netrin receptor activity; transcription coactivator activity; transmembrane signaling receptor activity; Developmental protein

Subcellular Location

axon; cytosol; plasma membrane

Expression

Found in axons of the central and peripheral nervous system; differentiated cell types of the intestine

Structure

Belongs to the immunoglobulin superfamily. DCC family; Contains 6 fibronectin type-III domains; Contains 4 Ig-like C2-type (immunoglobulin-like) domains

Alternative Nomenclature

DNA dependent protein kinase catalytic subunit antibody

DNA PK catalytic subunit antibody

DNA-PKcs antibody

DNAPK antibody

DNAPK catalytic subunit antibody

DNPK 1 antibody

Hyper radiosensitivity of murine scid mutation, complementing 1 antibody

HYRC 1 antibody

p350 antibody

p460 antibody

PKRDC antibody

Protein Kinase DNA Activated Catalytic Polypeptide antibody

XRCC 7 antibody