General Information
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Product
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CCR4-NOT Antibody
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Description
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Affinity Purified CCR (yeast CCR4/NOT complex component) homolog Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Caenorhabditis elegans
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Immunogen
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Synthetic peptide taken within amino acid region 50-100 on C. elegans CCR (yeast CCR4/NOT complex) protein.
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Accession #
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NCBI: NP_001023608.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.68 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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Immunoprecipitation
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1:250
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Western Blot
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1:500
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Protein
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Uniprot #
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Q8I4B4
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Overview
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Scaffolding component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.
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Molecular Function
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Developmental protein, Repressor
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Subcellular Location
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Cytoplasm > P-body; Nucleus
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Alternative Nomenclature
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CCR4-NOT transcription complex antibody
LENG2 Antibody
Leukocyte receptor cluster member 2 antibody
NOT3 (negative regulator of trasncription, yeast) homolog antibody
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