General Information

Product

Phospholipase A2 IIA Antibody Affinity Purified

Description

Affinity Purified Phospholipase A2, membrane associated Antibody

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 50-150 on human Phospholipase A2 membrane associated protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P14555

Overview

regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.

Molecular Function

Hydrolase

Subcellular Location

Membrane

Expression

Small intestine,heart,liver,lymph node,placenta & prostate.

Structure

Belongs to the phospholipase A2 family.

Alternative Nomenclature

EC 3.1.1.4 antibody

GIIC sPLA2 antibody

Group IIA phospholipase A2 antibody

membrane associated antibody

MOM1 antibody

Non pancreatic secretory phospholipase A2 antibody

NPSPLA2 antibody

Phosphatidylcholine 2-acylhydrolase 2A antibody

Phospholipase A2 antibody

PLA2 antibody

PLA2B antibody

PLA2G2A antibody

PLA2L antibody

PLA2S antibody

PLAS1 antibody

RASF A antibody

sPLA2 antibody

General Information

Product

BMP1 Antibody

Description

Affinity Purified Bone morphogenetic protein 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human BMP1 protein.

Accession #

NCBI:  NP_001190

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-0.56 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:2,000

ELISA

1:2,000

Western Blot

1:500

Protein

Uniprot #

P13497

Overview

Cleaves the C-terminal propeptides of procollagen I, II and II. Induces bone and cartilage formation.

Molecular Function

Chondrogenesis; Differentiation; Osteogenesis; Calcium, Zinc, Metal binding

Subcellular Location

trans-Golgie network; secreted; ECM

Expression

Ubiquitous

Structure

Belongs to peptidase M12A family. Contains 5 CUB domains and 2 EGF-like domains.

Alternative Nomenclature

Mammalian tolloid protein antibody

mTld antibody

OI13 antibody

PCOLC antibody

PCP2 antibody

Procollagen C endopeptidase antibody

TLD antibody

Tolloid, Drosophila, homolog of antibody

General Information

Product

GPCR GPR43 Antibody

Description

Affinity Purified Free fatty acid receptor 2 Antibody C-epitope

Verified Applications

DB, ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 280-330 on human free fatty acid receptor 2 protein.

Accession #

NCBI:  NP_005297.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.58-0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

O15552

Overview

G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family.

Molecular Function

G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Detected in whole wall and separated mucosa in the distal ileum and colon. Expressed by enteroendocrine cells expressing peptide YY (PYY) (at protein level).

Structure

Interacts with FCN1 (via Fibrinogen C-terminal domain).

Alternative Nomenclature

FFA2R antibody

free fatty acid activated receptor 2 antibody

Free fatty acid receptor 2 antibody

G-protein coupled receptor 43 antibody

GPR 43 antibody

General Information

Product

GPCR GPR43 Antibody

Description

Affinity Purified Free fatty acid receptor 2 Antibody Mid Region

Verified Applications

DB, ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-300 on human free fatty acid receptor 2 protein.

Accession #

NCBI:  NP_005297.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.58-0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Mid Region

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

O15552

Overview

G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family.

Molecular Function

G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Detected in whole wall and separated mucosa in the distal ileum and colon. Expressed by enteroendocrine cells expressing peptide YY (PYY) (at protein level).

Structure

Interacts with FCN1 (via Fibrinogen C-terminal domain).

Alternative Nomenclature

FFA2R antibody

free fatty acid activated receptor 2 antibody

Free fatty acid receptor 2 antibody

G-protein coupled receptor 43 antibody

GPR 43 antibody

General Information

Product

Glucose transporter GLUT2 Antibody

Description

Affinity Purified Solute carrier family 2 glucose transporter member 2 Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human GLUT2 protein.

Accession #

NCBI:  NP_112474.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:100

DB

1:8,000

ELISA

1:8,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P14246

Overview

Facilitative glucose transporter

Molecular Function

glucose transmembrane transporter activity

Subcellular Location

Membrane

Expression

In embryo, expressed in endoderm layer of yolk sac and liver primordium

Structure

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Alternative Nomenclature

liver antibody

Glucose Transporter 2 antibody

Glucose transporter type 2 liver antibody

Glucose transporter, liver/islet antibody

GLUT2 antibody

GTT2 antibody

SLC2A2 antibody

Solute carrier family 2 (facilitated glucose transporter) member 2 antibody

General Information

Product

Glucose transporter GLUT2 Antibody

Description

Affinity Purified Solute carrier family 2, facilitated glucose transporter member 2 Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino accid region 473-523 on mouse GLUT2 protein.

Accession #

NCBI:  NP_112474.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:100

DB

1:8,000

ELISA

1:8,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P19357

Overview

Insulin-regulated facilitative glucose transporter.

Molecular Function

glucose transmembrane transporter activity

Subcellular Location

Cell membrane, Cytoplasm, Membrane

Expression

Skeletal and cardiac muscles; brown and white fat.

Structure

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Alternative Nomenclature

liver antibody

Glucose Transporter 2 antibody

Glucose transporter type 2 liver antibody

Glucose transporter, liver/islet antibody

GLUT2 antibody

GTT2 antibody

SLC2A2 antibody

Solute carrier family 2 (facilitated glucose transporter) member 2 antibody

General Information

Product

PDE3B Antibody

Description

Affinity Purified cGMP-inhibited 3',5'-cyclic phosphodiesterase B Antibody

Verified Applications

CM, ELISA, ICC, IHC, IP, WB

Host

Goat

Species Cross Reactivity

Chicken, Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1060-1110 on human PDE3B protein.

Accession #

Gen Bank:  BAA09306

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:500

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:500

Immunofluorescence

1:500

Immunohistochemistry

1:500

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q13370

Overview

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3.

Molecular Function

Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding

Subcellular Location

Membrane; Multipass membrane protein

Expression

Abundant in adipose tissues.

Structure

Interacts with PIK3CG. Interacts with RAPGEF3 and PIK3R6 (By similarity).

Alternative Nomenclature

5''-cyclic phosphodiesterase B antibody

adipocyte cAMP phosphodiesterase cGMP inhibited antibody

AI847709 antibody

cAMP Phosphodiesterase, adipocyte, cGMP-inhibited antibody

CGIP1 antibody

CGIPDE B antibody

cGMP inhibited 3 5 cyclic phosphodiesterase B antibody

CGMP inhibited cAMP phophodiesterase antibody

cGMP-inhibited 3'' antibody

Cyclic GMP-inhibited phosphodiesterase B antibody

Cyclic nucleotide phosphodiesterase antibody

HcGIP1 antibody

Phosphodiesterase 3B cGMP inhibited antibody

General Information

Product

Bestrophin 1 Antibody

Description

Affinity Purified Bestrophin 1 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Dog, Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 530-580 on canine Bestrophin 1 protein.

Accession #

NCBI:  NP_001091014.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

A5H7G8

Overview

Forms calcium sensitive chloride channels. Highly permeable to bicarbonate.

Molecular Function

Ion transport; Sensory transduction; Transport; Vision

Subcellular Location

Cell membrane; Multi-pass membrane protein; Basolateral cell membrane

Expression

Predominantly expressed in the basolateral membrane of the retinal pigment epithelium

Structure

Tetramer or pentamers

Alternative Nomenclature

ARB antibody

BEST 1 antibody

BEST antibody

Best disease antibody

Best macular dystrophy antibody

Best1V1Delta2 antibody

BMD antibody

mBest1 antibody

RP50 antibody

TU15B antibody

Vitelliform macular dystrophy 2 antibody

Vitelliform macular dystrophy protein 2 antibody

VMD 2 antibody

General Information

Product

FNDC5 Antibody

Description

Affinity Purified Fibronectin type III domain-containing protein 5 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequences on human FNDC5 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q8K4Z2

Overview

Irisin: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA.

Molecular Function

Hormone

Subcellular Location

Cell membrane, Membrane, Peroxisome, Secreted

Expression

highly expressed in skeletal muscle, heart and brain.

Alternative Nomenclature

Fibronectin type III domain containing 5 antibody

FNDC 5 antibody

FRCP2 antibody

irisin antibody

General Information

Product

MINPP1 Antibody

Description

Affinity Purified Multiple inositol polyphosphate phosphatase-like protein Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-100 on rat MINPP1 protein.

Accession #

GenBank: BAD93056.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.51-0.62 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9UNW1

Subcellular Location

Endoplasmic reticulum lumen

Expression

Detected widely, with a high level of expression in kidney, liver and placenta.

Alternative Nomenclature

3 antibody

4 antibody

5)-tetrakisphosphate 3-phosphatase antibody

DKFZp564L2016 antibody

HIPER1 antibody

Inositol (1 antibody

inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase antibody

Minpp1 antibody

MINPP2 antibody

MIPP antibody

Multiple inositol polyphosphate phosphatase 1 antibody