General Information
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Product
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ABHD2 Antibody BIOTIN
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Description
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BIOTIN-Conjugated a/b hydrolase II Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 200-250 on mouse a/b hydrolase II protein.
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Accession #
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GenBank: AAQ12022.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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BIOTIN-Conjugated
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Purification Method
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Immobilized antigen affinity chromatography
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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Immunohistochemistry |
1:50-1:100 |
Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9QXM0
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Overview
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Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Involved in acrosomal reaction (PubMed:26989199). May also play a role in smooth muscle cells migration.
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Molecular Function
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Hydrolase, Serine esterase
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Subcellular Location
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Cell membrane By similarity; Single-pass type II membrane protein
Cytoplasmic vesicle › secretory vesicle › acrosome membrane
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Expression
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Widely expressed with higher expression in testis. Expressed by vascular smooth muscle cells, non vascular smooth muscle cells and heart.
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Structure
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Signal-anchor, Transmembrane, Transmembrane helix
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Alternative Nomenclature
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2210009N18Rik antibody
abhydrolase domain containing 2 antibody
alpha/beta hydrolase domain containing protein 2 antibody
HS1 2 antibody
LABH2 antibody
Lung alpha/beta hydrolase 2 antibody
PHPS1 2 antibody
protein PHPS1-2 antibody
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