General Information |
|
Product |
5HT1B Receptor Antibody FITC |
Description |
FITC-Conjugated 5 Hydroxytryptamine 1B receptor Antibody |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 160-260 on rat 5HT1B |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5-1.5 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:50,000 |
ELISA |
1:50,000 |
Immunoprecipitation |
1:200 |
Western Blot |
1:2,500-1:5,000 |
|
|
Uniprot # |
|
Overview |
G-protein coupled receptor for serotonin (5-hydroxytryptamine). Functions as a receptor for various drugs which cause conformational change upon ligand binding that triggers signaling via guanine nucleo-tide binding proteins and modulation of down-stream effectors like adenylate cyclase. Inhibits adenylate cyclase activity and activates phosphatidylinositol-calcium second messenger system that regulates release of intracellular Calcium ions. |
Molecular Function |
Drug binding, serotonin receptor activity, serotonin binding |
Subcellular Location |
Cell membrane; Multi-pass protein |
Structure |
Homodimer. Heterodimer with HTR1D |
Alternative Nomenclature |
HTR1DB antibody S12 antibody Serotonin 1D beta receptor antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
5HT1B-201AP | |||
|
P-5HT1B | |||
|
5HT1B-BIOTIN | |||
|
PC-5HT1B | |||
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