General Information
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Product
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ASXL3 Antibody BIOTIN
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Description
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BIOTIN-Conjugated Putative Polycomb group protein ASXL3 Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 2100-2150 on human Putative Polycomb group protein ASXL3.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5-1.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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BIOTIN-Conjugated
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Purification Method
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Immobilized antigen affinity chromatography
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:50,000
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Immunoprecipitation
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1:200
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Western Blot
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1:500-1:5,000
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Protein
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Uniprot #
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Q8C4A5
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Overview
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Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility.
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Molecular Function
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chromatin binding
DNA binding
metal ion binding
peroxisome proliferator activated receptor binding
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Subcellular Location
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Nuceus
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Structure
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Zinc-finger
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Alternative Nomenclature
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Additional sex combs-like protein 3
ASXL3
KIAA1713
Putative Polycomb group protein ASXL3
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