General Information |
|
Product |
iNOS Peptide |
Description |
Antigenic Blocking Peptide Nitric oxide synthase, inducible |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Synthetic peptide taken within amino acid region 1064-1114 on human inducible nitric oxide synthase protein. |
Specificity |
This antibody will detect both iNOS and iNOS2 protein. |
Accession # |
GenBank: BAA37123.1 |
|
|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
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|
Competition/Depletion assay |
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|
Uniprot # |
|
Overview |
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2. |
Molecular Function |
Arginine binding, FMN binding, iron ion binding, NADPH-hemoprotein reductase activity, nitric-oxide synthase activity, receptor binding, heme binding, NADP binding |
Subcellular Location |
cortical cytoskeleton; cytoplasm; cytosol; intracellular; nucleus; perinuclear region of cytoplasm; peroxisome |
Expression |
Expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Not expressed in the platelets. |
Structure |
Belongs to the NOS family. Contains 1 FAD-binding FR-type domain. Contains 1 flavodoxin-like domain. |
Alternative Nomenclature |
HEP NOS antibody Hepatocyte NOS antibody HEPNOS antibody inducible antibody Inducible nitric oxide synthase antibody Inducible NO synthase antibody Inducible NOS antibody INOS antibody MAC NOS antibody Macrophage NOS antibody Nitric oxide synthase 2 inducible macrophage antibody nitric oxide synthase 2A (inducible, hepatocytes) antibody Nitric oxide synthase antibody Nitric oxide synthase inducible antibody nitric oxide synthase, macrophage antibody NOS 2 antibody NOS antibody NOS2A antibody NOS2A, Inducible, Hepatocyte antibody Peptidyl-cysteine S-nitrosylase NOS2 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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iNOS-112AP | |||
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iNOS.112-BIOTIN | |||
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iNOS.112-FITC | |||
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PC-iNOS | |||
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