General Information

Product

BST2 Antibody

Description

Affinity Purified Bonemarrow stromal antigen 2 Antibody N-epitope

Verified Applications

ELISA, CM, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

N-epitope Synthetic peptide taken within amino acid region 1-50 on human Bonemarrow stromal antigen 2 protein.

Accession #

GenBank:  BAD96844

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.62 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:2,000

ELISA

1:2,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500-1:1,000

Protein

Uniprot #

Q10589

Overview

IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells.

Molecular Function

Antiviral defense; B-cell activation; Immunity; Innate immunity

Subcellular Location

Gogli apparatus, trans-golgi network; Cell membrane, Single-pass type II membrane protein. Lipid anchor, GPI anchor; Late endosome; Membrane raft; Cytoplasm; Apical cell membrane

Expression

Liver, lung, heart and placenta. Lower levels in pancreas, kidney, skeletal msucle and brain. Overexpressed in multiple myeloma cells. B-cells, T-cells, monocytes, NK cells and dendritic cells. Induced by type I interforns. Down regulated by viral antagonistic factors.

Structure

Parallel homodimer; disulfide linked. Cytoplasmic domain interacts with ARHGAP44 and MMP14.

Alternative Nomenclature

Bone marrow stromal antigen 2 antibody

Bone marrow stromal cell antigen 2 antibody

BST 2 antibody

CD 317 antibody

CD317 antigen antibody

HM1.24 antigen antibody

NPC A 7 antibody

Tetherin antibody

General Information

Product

BST2 Antibody

Description

Affinity Purified Bonemarrow stromal antigen 2 Antibody Mid-Region

Verified Applications

ELISA, CM, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Mid-Region Epitope Synthetic peptide taken within amino acid region 50-100 on human Bonemarrow stromal antigen 2 protein.

Accession #

GenBank:  BAD96844

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.62 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Mid-Region

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:2,000

ELISA

1:2,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500-1:1,000

Protein

Uniprot #

Q10589

Overview

IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells.

Molecular Function

Antiviral defense; B-cell activation; Immunity; Innate immunity

Subcellular Location

Gogli apparatus, trans-golgi network; Cell membrane, Single-pass type II membrane protein. Lipid anchor, GPI anchor; Late endosome; Membrane raft; Cytoplasm; Apical cell membrane

Expression

Liver, lung, heart and placenta. Lower levels in pancreas, kidney, skeletal msucle and brain. Overexpressed in multiple myeloma cells. B-cells, T-cells, monocytes, NK cells and dendritic cells. Induced by type I interforns. Down regulated by viral antagonistic factors.

Structure

Parallel homodimer; disulfide linked. Cytoplasmic domain interacts with ARHGAP44 and MMP14.

Alternative Nomenclature

Bone marrow stromal antigen 2 antibody

Bone marrow stromal cell antigen 2 antibody

BST 2 antibody

CD 317 antibody

CD317 antigen antibody

HM1.24 antigen antibody

NPC A 7 antibody

Tetherin antibody

General Information

Product

BST2 Antibody

Description

Affinity Purified Bonemarrow stromal antigen 2 Antibody C-epitope

Verified Applications

ELISA, CM, ICC, IF, IHC, IP, WB

Host

Rabbit

Immunogen

C-epitope Synthetic peptide taken within amino acid region 100-150 on human Bonemarrow stromal antigen 2 protein.

Accession #

GenBank:  BAD96844

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.62 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DOT Blot

1:2,000

ELISA

1:2,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500-1:1,000

Protein

Uniprot #

Q10589

Overview

IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells.

Molecular Function

Antiviral defense; B-cell activation; Immunity; Innate immunity

Subcellular Location

Gogli apparatus, trans-golgi network; Cell membrane, Single-pass type II membrane protein. Lipid anchor, GPI anchor; Late endosome; Membrane raft; Cytoplasm; Apical cell membrane

Expression

Liver, lung, heart and placenta. Lower levels in pancreas, kidney, skeletal msucle and brain. Overexpressed in multiple myeloma cells. B-cells, T-cells, monocytes, NK cells and dendritic cells. Induced by type I interforns. Down regulated by viral antagonistic factors.

Structure

Parallel homodimer; disulfide linked. Cytoplasmic domain interacts with ARHGAP44 and MMP14.

Alternative Nomenclature

Bone marrow stromal antigen 2 antibody

Bone marrow stromal cell antigen 2 antibody

BST 2 antibody

CD 317 antibody

CD317 antigen antibody

HM1.24 antigen antibody

NPC A 7 antibody

Tetherin antibody

General Information

Product

JunD Antibody Affinity Purified N-epitope

Description

Affinity Purified Djun Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

D. melanogaster

Immunogen

Synthetic peptide corresponding to unique sequence on Drosophila melangoaster Jun protein.

Accession #

GenBank:  AAA28650

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20°C for long term storage

Application Protocol

Confocal Microscopy

1:250

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Western Blot

1:500

Protein

Uniprot #

P18289

Overview

Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.

Molecular Function

Activator; Transcription regulation;

Subcellular Location

Nucleus

Expression

Expressed during embryonic development

Structure

AP-1/dJRA interacts with AP-1/dFra to form a dimer. The dFra-dJRA complex is bound more stably to the AP-1 site than either of the two proteins alone.

Alternative Nomenclature

Activator protein 1 antibody

AP 1 antibody

Transcription factor jun D antibody

General Information

Product

JunD Antibody Affinity Purified

Description

Affinity Purified Djun Antibody C-epitope

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

D. melanogaster

Immunogen

Synthetic peptide corresponding to unique sequence on Drosophila melangoaster Jun protein.

Accession #

Gen Bank: AAA28650

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20°C for long term storage

Application Protocol

Confocal Microscopy

1:250

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Western Blot

1:500

Protein

Uniprot #

P18289

Overview

Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.

Molecular Function

Activator; Transcription regulation;

Subcellular Location

Nucleus

Expression

Expressed during embryonic development

Structure

AP-1/dJRA interacts with AP-1/dFra to form a dimer. The dFra-dJRA complex is bound more stably to the AP-1 site than either of the two proteins alone.

Alternative Nomenclature

Activator protein 1 antibody

AP 1 antibody

Transcription factor jun D antibody

General Information

Product

SARA Antibody Affinity Purified

Description

Affinity Purified Smad anchor for receptor activation (SARA) mRNA, complete cds Antibody Mid-Region

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

D. melanogaster

Immunogen

Synthetic peptide taken within amino acid region 320-370 on SARA protein.

Accession #

GenBank:  AF104305.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Mid-Region

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9YHB9

Molecular Function

Metal ion binding, Receptor

Alternative Nomenclature

CG15667 antibody

LD33044p antibody

Madh-interacting protein antibody

MADHIP antibody

Mothers against decapentaplegic homolog-interacting protein antibody

Novel serine protease antibody

NSP antibody

Receptor activation anchor antibody

SAR1 antibody

SARA1 antibody

smad anchor for Receptor Activation antibody

SMADIP antibody

ZFYVE9 antibody

Zinc finger FYVE domain-containing protein 9 antibody

General Information

Product

SARA Antibody Affinity Purified

Description

Affinity Purified Smad anchor for receptor activation (SARA) mRNA, complete cds Antibody C-epitope

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

D. melanogaster

Immunogen

Synthetic peptide taken within amino acid region 1040-1090 on SARA protein.

Accession #

GenBank:  AF104305.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9YHB9

Molecular Function

Metal ion binding, Receptor

Alternative Nomenclature

CG15667 antibody

LD33044p antibody

Madh-interacting protein antibody

MADHIP antibody

Mothers against decapentaplegic homolog-interacting protein antibody

Novel serine protease antibody

NSP antibody

Receptor activation anchor antibody

SAR1 antibody

SARA1 antibody

smad anchor for Receptor Activation antibody

SMADIP antibody

ZFYVE9 antibody

Zinc finger FYVE domain-containing protein 9 antibody

General Information

Product

SARA Antibody Affinity Purified

Description

Affinity Purified Smad anchor for receptor activation (SARA) mRNA, complete cds Antibody N-epitope

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

D. melanogaster

Immunogen

Synthetic peptide taken within amino acid region 260-300 on SARA protein.

Accession #

GenBank:  AF104305.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9YHB9

Molecular Function

Metal ion binding, Receptor

Alternative Nomenclature

CG15667 antibody

LD33044p antibody

Madh-interacting protein antibody

MADHIP antibody

Mothers against decapentaplegic homolog-interacting protein antibody

Novel serine protease antibody

NSP antibody

Receptor activation anchor antibody

SAR1 antibody

SARA1 antibody

smad anchor for Receptor Activation antibody

SMADIP antibody

ZFYVE9 antibody

Zinc finger FYVE domain-containing protein 9 antibody

General Information

Product

Phospho-p27 KIP1 Antibody

Description

Affinity Purified Phosphorylated Cyclin-dependent kinase inhibitor p27kip1 Antibody Extreme C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Chicken, Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 148-198 on human Cyclin-dependent kinase inhibitor 1 (p27, KIP1) protein.

Accession #

GenBank: AAH01971.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Extreme C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:250

Protein

Uniprot #

Q9NYG6

Overview

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.

Molecular Function

Cyclin-dependent protein serine/threonine kinase inhibitor activity, kinase activity

Subcellular Location

Nucleus

Expression

Expressed in all tissues tested. Highest levels in skeletal muscle, lowest in liver and kidney.

Structure

Forms a ternary complex with CCNE1/CDK2/CDKN1B. Interacts directly with CCNE1; the interaction is inhibited by CDK2-dependent phosphorylation on Thr-187. Interacts with COPS5, subunit of the COP9 signalosome complex.

Alternative Nomenclature

AA408329 antibody

AI843786 antibody

CDKN 1B antibody

CDKN 4 antibody

Cyclin Dependent Kinase Inhibitor 1B antibody

Cyclin dependent kinase inhibitor p27 antibody

KIP 1 antibody

MEN1B antibody

MEN4 antibody

p27 antibody

p27 Kip1 antibody

P27-like cyclin-dependent kinase inhibitor antibody

General Information

Product

Phospho-p27 KIP1 Antibody

Description

Affinity Purified Phosphorylated Cyclin-dependent kinase inhibitor p27kip1 Antibody N-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Chicken, Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 143-193 on human Cyclin-dependent kinase inhibitor 1 (p27, KIP1) protein.

Accession #

GenBank: AAH01971.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:250

Protein

Uniprot #

Q9NYG6

Overview

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.

Molecular Function

Cyclin-dependent protein serine/threonine kinase inhibitor activity, kinase activity

Subcellular Location

Nucleus

Expression

Expressed in all tissues tested. Highest levels in skeletal muscle, lowest in liver and kidney.

Structure

Forms a ternary complex with CCNE1/CDK2/CDKN1B. Interacts directly with CCNE1; the interaction is inhibited by CDK2-dependent phosphorylation on Thr-187. Interacts with COPS5, subunit of the COP9 signalosome complex.

Alternative Nomenclature

AA408329 antibody

AI843786 antibody

CDKN 1B antibody

CDKN 4 antibody

Cyclin Dependent Kinase Inhibitor 1B antibody

Cyclin dependent kinase inhibitor p27 antibody

KIP 1 antibody

MEN1B antibody

MEN4 antibody

p27 antibody

p27 Kip1 antibody

P27-like cyclin-dependent kinase inhibitor antibody