General Information |
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Product |
HMGB1 Positive Control |
Description |
Western Blot Positive Control High mobility group protein B1 |
Verified Applications |
WB |
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Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
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Uniprot # |
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Overview |
Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. |
Molecular Function |
bubble DNA binding chemoattractant activity C-X-C chemokine binding cytokine activity damaged DNA binding DNA binding, bending DNA binding transcription factor activity DNA polymerase binding double-stranded DNA binding four-way junction DNA binding integrin binding lipopolysaccharide binding lyase activity phosphatidylserine binding RAGE receptor binding repressing transcription factor binding RNA binding single-stranded DNA binding supercoiled DNA binding transcription factor binding |
Subcellular Location |
Extracellular region or secreted, nucleus, endosome, plasma membrane, chromosome, cytoplasm, endoplasmic reticulum-golgi intermediate compartment |
Expression |
Ubiquituous. Expressed in platelets. |
Structure |
Belongs to the HMGB family. |
Alternative Nomenclature |
Amphoterin antibody Chromosomal protein, nonhistone, HMG1 antibody High mobility group box 1 antibody High mobility group protein 1 antibody High mobility group protein B1 antibody high-mobility group (nonhistone chromosomal) protein 1 antibody HMG-1 antibody HMG3 antibody HMGB 1 antibody NONHISTONE CHROMOSOMAL PROTEIN HMG1 antibody SBP 1 antibody Sulfoglucuronyl carbohydrate binding protein antibody |
Protein information supplied by UniProt.
Fabgennix HMGB1 Antibody has been used in 1 Publication |
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Chellappan, Rajeshwari et al. "SRI-42127, a novel small molecule inhibitor of the RNA regulator HuR, potently attenuates glial activation in a model of lipopolysaccharide-induced neuroinflammation." Glia 70.1 (2022). PMID: 34533864
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Immunocytochemistry; Mouse |
Publishing research using HMGB1-101AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
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HMGB1-101AP | |||
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HMGB1-BIOTIN | |||
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HMGB1-FITC | |||
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P-HMGB1 | |||
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