General Information |
|
Product |
WDR5 Antibody BIOTIN |
Description |
BIOTIN-Conjugated WD repeat-containing protein 5 Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Arabidopsis thaliana, Human, Monkey, Mouse, Rat Predicted: Chicken, Cow, Dog, Pig, Xenopus laevis, Zebrafish |
Immunogen |
Synthetic peptide:
DVKTGKCLKTLPAHSDPV
corresponding to amino acids 157-174 of Human WDR5 protein. |
Accession # |
NCBI: NP_060058.2 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.67 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunohistochemistry | 1:100 |
Immunoprecipitation | 1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. |
Molecular Function |
Chromatin regulator |
Subcellular Location |
Nucleus |
Structure |
Interacts with PAXBP1; the interaction is direct and links a WDR5-containing histone methyltransferase complex to PAX7 and PAX3. Interacts with HCFC1. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. |
Alternative Nomenclature |
2410008O07Rik antibody AA408785 antibody AA960360 antibody Big antibody BIG3 antibody BMP2 induced 3 kb gene protein antibody MGC114572 antibody OTTHUMP00000162494 antibody SWD3 Set1c WD40 repeat protein homolog antibody WD repeat-containing protein 5 antibody WD repeat-containing protein BIG-3 antibody WDR 5 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-WDR5 | |||
|
WDR5-101AP | |||
|
WDR5-FITC | |||
|
PC-WDR5 | |||
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