General Information
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Product
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TDRD7 Antibody
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Description
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Tudor domain-containing protein 7 isoform 1 Antibody
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within the last 50 amino acids of the C-terminal end of TDRD7 protein.
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Accession #
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NCBI: NP_055105.2
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.59-0.62 µg/µl in antibody stabilization buffer
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Western Blot
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1:500
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Protein
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Uniprot #
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Q8NHU6
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Overview
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Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis.
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Molecular Function
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mRNA binding
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Subcellular Location
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cytoplasm (Note: Localizes to cytoplasmic RNA granules. Present in chromatoid body (CB) of spermatids (mammalian counterpart of germplasm, pole plasm or polar granules in Drosophila germ cells), also named processing bodies (P-bodies) in somatic cells. De
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Alternative Nomenclature
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KIAA1529 antibody
PCTAIRE 2 antibody
PCTAIRE2BP antibody
RP11-508D10.1 antibody
TDRD 7 antibody
TrAP antibody
Tudor domain containing 7 antibody
Tudor repeat associator with PCTAIRE 2 antibody
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