General Information |
|
Product |
Apelin Antibody BIOTIN |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Rat Predicted: Mouse |
Immunogen |
Synthetic peptide taken within amino acid region 25-77 on human Apelin protein. |
Accession # |
NCBI: NP_059109 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
BIOTIN-Conjugated |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:50,000 |
Immunohistochemistry | 1:50-1:150 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Endogenous ligand for APJ, an alternative coreceptor with CD4 for HIV-1 infection. Inhibits HIV-1 entry in cells coexpressing CD4 and APJ. Apelin-36 has a greater inhibitory activity on HIV infection than other synthetic apelin derivatives. The oral intake in the colostrum and the milk could have a role in the modulation of the immune responses in neonates. May also have a role in the central control of body fluid homeostasis by influencing AVP release and drinking behavior. |
Molecular Function |
G-protein coupled receptor binding, receptor binding |
Subcellular Location |
Secreted |
Expression |
Expressed in the brain with highest levels in the frontal cortex, thalamus, hypothalamus and midbrain. Secreted by the mammary gland into the colostrum and the milk. |
Structure |
Belongs to the apelin family. |
Alternative Nomenclature |
AGTRL1 ligand antibody APEL antibody Apelin-13 antibody APJ endogenous ligand antibody Apln antibody XNPEP2 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
APEL-101AP | |||
|
APEL-FITC | |||
|
P-APEL | |||
|
PC-APEL | |||
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