General Information

Description

Affinity Purified Estrogen Receptor Antibody Mid Region

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Rat

Immunogen

Synthetic peptide taken within amino acid region 520-570 on human Estrogen receptor alpha protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Mid Region

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P03372

Overview

Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues

Molecular Function

Activator, Receptor

Subcellular Location

Cell membrane, Cytoplasm, Golgi apparatus, Membrane, Nucleus

Expression

Widely expressed. Isoform 3 is not expressed in the pituitary gland

Structure

Belongs to the nuclear hormone receptor family. NR3 subfamily

Alternative Nomenclature

DKFZp686N23123 antibody

ER alpha antibody

ER antibody

Era antibody

ESR antibody

ESR1 antibody

ESRA antibody

Estradiol receptor antibody

Estrogen nuclear receptor alpha antibody

Estrogen receptor 1 antibody

Estrogen receptor antibody

ESTRR antibody

Major ORF antibody

NR3A1 antibody

Nuclear receptor subfamily 3 group A member 1 antibody

General Information

Product

Estrogen Receptor alpha Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 545-595 on human Estrogen receptor alpha protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P03372

Overview

Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

Molecular Function

Activator, Receptor

Subcellular Location

Cell membrane, Cytoplasm, Golgi apparatus, Membrane, Nucleus

Expression

Widely expressed. Isoform 3 is not expressed in the pituitary gland

Structure

Belongs to the nuclear hormone receptor family. NR3 subfamily

Alternative Nomenclature

DKFZp686N23123 antibody

ER alpha antibody

ER antibody

Era antibody

ESR antibody

ESR1 antibody

ESRA antibody

Estradiol receptor antibody

Estrogen nuclear receptor alpha antibody

Estrogen receptor 1 antibody

Estrogen receptor antibody

ESTRR antibody

Major ORF antibody

NR3A1 antibody

Nuclear receptor subfamily 3 group A member 1 antibody

General Information

Product

hCG beta Antibody

Description

Affinity Purified Choriogonadotropin subunit beta Antibody C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 131-149 on human Chorionic gonaotropin beta protein.

Specificity

This antibody will detect CGB1, CGB2, CGB5, CGB7, CGB8.

Accession #

NCBI:  NP_203695.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.63 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

A6NKQ9

Overview

Stimulates ovaries to synthesize the steriods that are essential for the maintenance of pregnancy

Molecular Function

Hormone

Subcellular Location

Secreted

Expression

Expressed in placenta, testis and pituitary.

Structure

Belongs to glycoprotein hormones subunit beta family

Alternative Nomenclature

CG beta antibody

CGB 3 antibody

CGB 5 antibody

CGB 7 antibody

CGB antibody

CGB8 antibody

Choriogonadotropin subunit beta antibody

Chorionic gonadotrophin chain beta antibody

Chorionic gonadotropin beta polypeptide antibody

Chorionic gonadotropin beta subunit antibody

hCGB antibody

Human Chorionic Gonadotropin antibody

General Information

Product

hCG beta Antibody

Description

Affinity Purified Choriogonadotropin subunit beta Antibody Extreme C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 142-165 on human Chorionic gonaotropin beta protein.

Specificity

This antibody will detect CGB1, CGB2, CGB5, CGB7, CGB8.

Accession #

NCBI:  NP_203695.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.63 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Extreme C-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

A6NKQ9

Overview

Stimulates ovaries to synthesize the steriods that are essential for the maintenance of pregnancy

Molecular Function

Hormone

Subcellular Location

Secreted

Expression

Expressed in placenta, testis and pituitary.

Structure

Belongs to glycoprotein hormones subunit beta family

Alternative Nomenclature

CG beta antibody

CGB 3 antibody

CGB 5 antibody

CGB 7 antibody

CGB antibody

CGB8 antibody

Choriogonadotropin subunit beta antibody

Chorionic gonadotrophin chain beta antibody

Chorionic gonadotropin beta polypeptide antibody

Chorionic gonadotropin beta subunit antibody

hCGB antibody

Human Chorionic Gonadotropin antibody

General Information

Product

hCG beta 2 Antibody

Description

Affinity Purified Choriogonadotropin subunit beta 2 Antibody N-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 50-100 on human choriogonadotropin subunit beta variant 2 protein.

Specificity

This antibody will detect CGB2 only.

Accession #

GenBank: AAH69367.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.63 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

H9KV56

Overview

Stimulates ovaries to synthesize the steriods that are essential for the maintenance of pregnancy

Molecular Function

Hormone

Subcellular Location

Secreted

Expression

Placenta

Structure

Belongs to glycoprotein hormones subunit beta family

Alternative Nomenclature

CG beta antibody

CGB antibody

CGB2 antibody

Chorionic gonadotropin beta 2 subunit antibody

Chorionic gonadotropin beta chain antibody

Chorionic gonadotropin beta polypeptide antibody

hCGB2 antibody

Human Chorionic Gonadotropin antibody

General Information

Product

hCG beta 2 Antibody

Description

Affinity Purified Choriogonadotropin subunit beta 2 Antibody C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 82-132 on human choriogonadotropin subunit beta variant 2 protein.

Specificity

This antibody will detect CGB2 only.

Accession #

GenBank: AAH69367.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.63 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

H9KV56

Overview

Stimulates ovaries to synthesize the steriods that are essential for the maintenance of pregnancy

Molecular Function

Hormone

Subcellular Location

Secreted

Expression

Placenta

Structure

Belongs to glycoprotein hormones subunit beta family

Alternative Nomenclature

CG beta antibody

CGB antibody

CGB2 antibody

Chorionic gonadotropin beta 2 subunit antibody

Chorionic gonadotropin beta chain antibody

Chorionic gonadotropin beta polypeptide antibody

hCGB2 antibody

Human Chorionic Gonadotropin antibody

General Information

Product

Apelin Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Rat

Predicted: Mouse

Immunogen

Synthetic peptide taken within amino acid region 25-77 on human Apelin protein.

Accession #

NCBI:  NP_059109

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9ULZ1

Overview

Endogenous ligand for APJ, an alternative coreceptor with CD4 for HIV-1 infection. Inhibits HIV-1 entry in cells coexpressing CD4 and APJ. Apelin-36 has a greater inhibitory activity on HIV infection than other synthetic apelin derivatives. The oral intake in the colostrum and the milk could have a role in the modulation of the immune responses in neonates. May also have a role in the central control of body fluid homeostasis by influencing AVP release and drinking behavior.

Molecular Function

G-protein coupled receptor binding, receptor binding

Subcellular Location

Secreted

Expression

Expressed in the brain with highest levels in the frontal cortex, thalamus, hypothalamus and midbrain. Secreted by the mammary gland into the colostrum and the milk.

Structure

Belongs to the apelin family.

Alternative Nomenclature

AGTRL1 ligand antibody

APEL antibody

Apelin-13 antibody

APJ endogenous ligand antibody

Apln antibody

XNPEP2 antibody

General Information

Product

Apelin Receptor Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 330-377 rat Apelin receptor protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9JHG3

Overview

Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.

Molecular Function

Developmental protein, G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane, Multi-pass membrane protein

Expression

Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon.

Structure

Transmembrane, Transmembrane helix

Alternative Nomenclature

AGTRL1 ligand antibody

APEL antibody

Apelin-13 antibody

APJ endogenous ligand antibody

Apln antibody

XNPEP2 antibody

General Information

Product

Apelin Receptor Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Rat

Immunogen

Synthetic peptide taken within amino acid region 150-200 human Apelin receptor protein.

Accession #

NCBI:  NP_005152

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P35414

Overview

Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.

Molecular Function

Developmental protein, G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane, Multi-pass membrane protein

Expression

Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon.

Structure

Transmembrane, Transmembrane helix

Alternative Nomenclature

AGTRL1 ligand antibody

APEL antibody

Apelin-13 antibody

APJ endogenous ligand antibody

Apln antibody

XNPEP2 antibody

General Information

Product

PACAP Antibody

Description

Affinity Purified Pituitary adenylate cyclase-activating polypeptide Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 125-176 on human Pituitary adenylate cyclase-activating polypeptide protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000

Protein

Uniprot #

P18509

Overview

Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells.

Molecular Function

neuropeptide hormone activity

peptide hormone receptor binding

pituitary adenylate cyclase activating polypeptide activity

pituitary adenylate cyclase-activating polypeptide receptor binding

receptor binding

signal transducer activity, downstream of receptor

Subcellular Location

Secreted

Expression

Interacts with ADCYAP1R1 (via N-terminal extracellular domain).

Structure

Belongs to the glucagon family.

Alternative Nomenclature

adenylate cyclase activating polypeptide 1 (pituitary) antibody

PACAP antibody

PACAP-related peptide antibody

Pituitary adenylate cyclase-activating polypeptide 27 antibody

Pituitary adenylate cyclase-activating polypeptide 38 antibody

Pituitary adenylate cyclase-activating polypeptide antibody

prepro-PACAP antibody

PRP-48 antibody