General Information
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Product
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Brk Positive Control
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Description
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Western Blot Positive Control Protein-Tyrosine Kinase 6 isoform
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Verified Applications
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WB
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Accession #
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NCBI: NP_033210
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Physical Properties
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Quantity
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5 Applications
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Volume
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Inquire
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Form
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Western Blot Positive Control
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Storage
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-20⁰C for long term storage
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Application Protocol
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Western Blot
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1:2,500-1:5,000
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Protein
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Uniprot #
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Q64434
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Molecular Function
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ATP binding
identical protein binding
non-membrane spanning protein tyrosine kinase activity
protein tyrosine kinase activity
signaling receptor binding
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Subcellular Location
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Nucleus, Cytoplasm, Membrane, Ruffle
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Expression
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Expressed only in epithelial tissues, including the skin and lining of the alimentary canal. Restricted to the cell layers immediately above the proliferative cell zone in these epithelia.
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Structure
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The SH3 domain plays a major role in substrate interactions. The SH2 domain of PTK6 plays a role in protein-protein interactions, but is likely more important for the regulation of catalytic activity (By similarity).
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Alternative Nomenclature
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Breast tumor kinase antibody
Protein tyrosine kinase 6 antibody
Ptk6 antibody
Tyrosine-protein kinase BRK antibody
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