General Information
|
|
Product
|
AKT1 Peptide
|
Description
|
Antigenic Blocking Peptide RAC-alpha serine/threonine-protein kinase
|
Verified Applications
|
Immmunodepletion, Competition Assay
|
Peptide Description
|
Synthetic peptide taken within the last 50 amino acid on human RAC-alpha serine/threonine-protein kinase protein. |
Accession #
|
GenBank: AAA36539
|
Physical Properties
|
|
Quantity
|
250 µg
|
Volume
|
100 µl
|
Form
|
Antigenic Blocking Peptide
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
|
Competition/Depletion assay
|
Refer to competition assay protocol
|
Protein
|
|
Uniprot #
|
P31749
|
Overview
|
One of 3 serine/threonine-protein kinases (AKT1-AKT3) regulates many processes including metabolism, proliferation, cell survival, growth and angiogenesis.
|
Molecular Function
|
Developmental protein; Kinase; Serine/threonine-protein kinase; Transferase
|
Subcellular Location
|
Cytoplasm; Nucleus; Cell membrane
|
Expression
|
Expressed in prostate cancer and all human cell types.
|
Structure
|
Interacts with and phosphorylated by PDPK1. Interacts with several proteins invovled in phosphorylation and ubiquitination
|
Alternative Nomenclature
|
PKB antibody
Protein Kinase B Alpha antibody
RAC Serine/Threonine Protein Kinase antibody
vAKT Murine Thymoma Viral Oncogene Homolog 1 antibody
|