General Information

Product

PAX2 isoform a + e Antibody

Description

Affinity Purified Paired box protein Pax-2 isoform a and Pax-2 isoform e Antibody N-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 200-220 on human PAX2 isoform d protein.

Specificity

This antibody will detect Pax-2 isoform a and Pax-2 isoform e. Will not detect other Pax-2 isoforms.

Accession #

NCBI:  NP_003978.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75-0.95 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q02962

Overview

Probable transcription factor that may have a role in kidney cell differentiation. Has a critical role in the development of the urogenital tract, the eyes, and the CNS.

Molecular Function

Developmental protein, core promoter proximal region sequence-specific DNA binding, DNA binding

Subcellular Location

Nucleus

Expression

Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system.

Structure

Mainly in fetal kidney and juvenile nephrogenic rests.

Alternative Nomenclature

Paired box 2 antibody

Paired box gene 2 antibody

paired box protein 2 antibody

Paired box protein Pax 2 antibody

Pax 2 antibody

General Information

Product

PAX2 isoform a + e Antibody

Description

Affinity Purified Paired box protein Pax-2 isoform a and Pax-2 isoform e Antibody C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 205-235 on human PAX2 isoform d protein.

Specificity

This antibody will detect Pax-2 isoform a and Pax-2 isoform e. Will not detect other Pax-2 isoforms.

Accession #

NCBI:  NP_003978.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75-0.95 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q02962

Overview

Probable transcription factor that may have a role in kidney cell differentiation. Has a critical role in the development of the urogenital tract, the eyes, and the CNS.

Molecular Function

Developmental protein, core promoter proximal region sequence-specific DNA binding, DNA binding

Subcellular Location

Nucleus

Expression

Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system.

Structure

Mainly in fetal kidney and juvenile nephrogenic rests.

Alternative Nomenclature

Paired box 2 antibody

Paired box gene 2 antibody

paired box protein 2 antibody

Paired box protein Pax 2 antibody

Pax 2 antibody

General Information

Product

PAX1 Antibody

Description

Affinity Purified Paired Box Protein 

Pax-1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Rat

Immunogen

Synthetic peptide corresponding to unique sequence within amino acid region 210-260 on human PAX1 protein.

Accession #

NCBI: NP_006183.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75-0.95 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P15863

Overview

A transcriptional activator that may serve a function in the formation of segmented structures of the embryo.  Also may serve an important function in the normal development of the vertebral column.

Molecular Function

DNA binding, Activator, Developmental protein

Subcellular Location

Nucleus

Alternative Nomenclature

HUP48 antibody

OTTHUMP00000030407 antibody

Paired box 1 antibody

Paired domain gene HuP48 antibody

PAX 1 antibody

General Information

Product

FXIIIA Antibody

Description

Affinity Purified Blood coagulation factor XIII a subunit Antibody Multi-epitope

Verified Applications

CM, ELISA, ICC, IHC, IF, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Multi-epitope synthetic peptides were used: amino acid range 1-50 and 700-732.  A mixture of synthetic peptides used for FXIIIA-101AP and FXIIIA-112AP.

Accession #

GenBank: AAA52415.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P00488

Overview

Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.

Molecular Function

Metal ion binding; Protein-glutamine gamma-glutamyltransferase activity

Subcellular Location

Cytoplasm. Secreted

Structure

Tetramer of two A chains and two B chains.

Alternative Nomenclature

Coagulation factor XIII A chain antibody

F13A antibody

Factor XIIIA antibody

Fibrin stabilizing factor, A subunit antibody

Fibrinoligase antibody

FSF, A subunit antibody

TGase antibody

Transglutaminase A chain antibody

Transglutaminase. plasma antibody

General Information

Product

hopQ Antibody

Description

Affinity Purified hopQ H. Pylori Antibody

Verified Applications

CM, ELISA, ICC, IF, IP, IHC, WB

Host

Rabbit

Species Cross Reactivity

Heliobacter pylori

Immunogen

Heat killed and denatured Heliocobacter pylori extracts

Accession #

Accession: WP_202143412

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.80-1.35 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

ELISA

1:5,000

Immunocytochemistry

1:200

Immunofluorescence

1:300

Immunohistochemistry

1:200

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

J0TJV0

Overview

Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation. Negatively regulates the induction of IFNB in response to RNA virus infection.

Molecular Function

polyubiquitin binding, Rab GTPase binding, protein C-terminus binding

Subcellular Location

Cytoplasm › perinuclear region. Golgi apparatus. Golgi apparatus › trans-Golgi network. Cytoplasmic vesicle ›autophagosome. Cytoplasmic vesicle. Recycling endosome

Expression

Present in aqueous humor of the eye (at protein level). Highly expressed in trabecular meshwork. Expressed nonpigmented ciliary epithelium, retina, brain, adrenal cortex, fetus, lymphocyte, fibroblast, skeletal muscle, heart, liver, brain and placenta.

Structure

Interacts with HD, Rab8 (RAB8A and/or RAB8B) (active GTP-bound form), GTF3A, TRAF3, TBK1, MYO6 and TFRC. Binds to linear ubiquitin chains. Interacts with LC3 family members MAP1LC3A, MAP1LC3B, GABARAP, GABARAPL1 and GABARAPL2; OPTN phosphorylation increas

Alternative Nomenclature

H. pylori antibody

General Information

Product

Outer membrane protein 26 Antibody

Description

Affinity Purified Outer membrane protein 26 H. Pylori Antibody

Verified Applications

CM, ELISA, ICC, IF, IP, IHC, WB

Host

Rabbit

Species Cross Reactivity

Heliobacter pylori

Immunogen

Heat killed and denatured Heliocobacter pylori extracts.

Accession #

Accession: WP_097717672

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.80-1.35 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

ELISA

1:5,000

Immunocytochemistry

1:200

Immunofluorescence

1:300

Immunohistochemistry

1:200

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

J0NP37

Overview

Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation. Negatively regulates the induction of IFNB in response to RNA virus infection.

Molecular Function

polyubiquitin binding, Rab GTPase binding, protein C-terminus binding

Subcellular Location

Cytoplasm › perinuclear region. Golgi apparatus. Golgi apparatus › trans-Golgi network. Cytoplasmic vesicle ›autophagosome. Cytoplasmic vesicle. Recycling endosome

Expression

Present in aqueous humor of the eye (at protein level). Highly expressed in trabecular meshwork. Expressed nonpigmented ciliary epithelium, retina, brain, adrenal cortex, fetus, lymphocyte, fibroblast, skeletal muscle, heart, liver, brain and placenta.

Structure

Interacts with HD, Rab8 (RAB8A and/or RAB8B) (active GTP-bound form), GTF3A, TRAF3, TBK1, MYO6 and TFRC. Binds to linear ubiquitin chains. Interacts with LC3 family members MAP1LC3A, MAP1LC3B, GABARAP, GABARAPL1 and GABARAPL2; OPTN phosphorylation increas

Alternative Nomenclature

H. pylori antibody

General Information

Product

CD10 Antibody

Description

Affinity Purified Neprilysin Antibody Multi-epitope

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Multi-epitope synthetic peptides were used. A mixture of synthetic peptide taken within amino acid regions: 100-150, 200-250, 360-410, 450-500 and 700-750 on human Neprilysin protein.

Accession #

NCBI: NP_009218

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.72-0.78 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Multi-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Immunoprecipitation

1:250

Western Blot

1:500

Protein

Uniprot #

P08473

Overview

Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. angiotensin maturation; cellular response to UV; replicative senescence

Molecular Function

Hydrolase, Metalloprotease, Protease

Subcellular Location

Cell membrane, Membrane

Expression

Adipose tissue; duodenum; kidney; small intestine

Structure

Belongs to the peptidase M13 family

Alternative Nomenclature

Atriopeptidase antibody

CALLA antibody

CD10 antibody

Common acute lymphocytic leukemia antigen antibody

DKFZp686O16152 antibody

EC 3.4.24.11 antibody

Enkephalinase antibody

EPN antibody

gp100 antibody

Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) antibody

Membrane metallo endopeptidase antibody

MGC126681 antibody

MGC126707 antibody

MME antibody

NEP antibody

Neprilysin antibody

Neutral endopeptidase antibody

SFE antibody

Skin fibroblast elastase antibody

General Information

Product

CD10 Antibody

Description

Affinity Purified Neprilysin Antibody Mid Region

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 360-410 on human Neprilysin protein.

Accession #

NCBI: NP_009218

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.72-0.78 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Mid Region

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Immunoprecipitation

1:250

Western Blot

1:500

Protein

Uniprot #

P08473

Overview

Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. angiotensin maturation; cellular response to UV; replicative senescence

Molecular Function

Hydrolase, Metalloprotease, Protease

Subcellular Location

Cell membrane, Membrane

Expression

Adipose tissue; duodenum; kidney; small intestine

Structure

Belongs to the peptidase M13 family

Alternative Nomenclature

Atriopeptidase antibody

CALLA antibody

CD10 antibody

Common acute lymphocytic leukemia antigen antibody

DKFZp686O16152 antibody

EC 3.4.24.11 antibody

Enkephalinase antibody

EPN antibody

gp100 antibody

Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) antibody

Membrane metallo endopeptidase antibody

MGC126681 antibody

MGC126707 antibody

MME antibody

NEP antibody

Neprilysin antibody

Neutral endopeptidase antibody

SFE antibody

Skin fibroblast elastase antibody

General Information

Product

CD10 Antibody

Description

Affinity Purified Neprilysin Antibody Extreme N-epitope

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 100-150 on human Neprilysin protein.

Accession #

NCBI: NP_009218

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.72-0.78 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Extreme N-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Immunoprecipitation

1:250

Western Blot

1:500

Protein

Uniprot #

P08473

Overview

Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. angiotensin maturation; cellular response to UV; replicative senescence

Molecular Function

Hydrolase, Metalloprotease, Protease

Subcellular Location

Cell membrane, Membrane

Expression

Adipose tissue; duodenum; kidney; small intestine

Structure

Belongs to the peptidase M13 family

Alternative Nomenclature

Atriopeptidase antibody

CALLA antibody

CD10 antibody

Common acute lymphocytic leukemia antigen antibody

DKFZp686O16152 antibody

EC 3.4.24.11 antibody

Enkephalinase antibody

EPN antibody

gp100 antibody

Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) antibody

Membrane metallo endopeptidase antibody

MGC126681 antibody

MGC126707 antibody

MME antibody

NEP antibody

Neprilysin antibody

Neutral endopeptidase antibody

SFE antibody

Skin fibroblast elastase antibody

General Information

Product

CD10 Antibody

Description

Affinity Purified Neprilysin Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Recombinant CD10 protein.

Accession #

NCBI: NP_009218

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Immunoprecipitation

1:250

Western Blot

1:500

Protein

Uniprot #

P08473

Overview

Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. angiotensin maturation; cellular response to UV; replicative senescence.

Molecular Function

Hydrolase, Metalloprotease, Protease

Subcellular Location

Cell membrane, Membrane

Expression

Adipose tissue; duodenum; kidney; small intestine

Structure

Belongs to the peptidase M13 family

Alternative Nomenclature

Atriopeptidase antibody

CALLA antibody

CD10 antibody

Common acute lymphocytic leukemia antigen antibody

DKFZp686O16152 antibody

EC 3.4.24.11 antibody

Enkephalinase antibody

EPN antibody

gp100 antibody

Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) antibody

Membrane metallo endopeptidase antibody

MGC126681 antibody

MGC126707 antibody

MME antibody

NEP antibody

Neprilysin antibody

Neutral endopeptidase antibody

SFE antibody

Skin fibroblast elastase antibody