General Information
Product
RPE65 Antibody FITC-Conjugated
Verified Applications
ELISA, IP, WB
Host
Rabbit
Species Cross Reactivity
Bovine, Human, Mouse, Rat
Immunogen
Synthetic peptide corresponding to unique amino acid sequence on mouse RPE65 protein.
Accession #
GenBank: AAL01119.1
Physical Properties
Quantity
100 µg
Volume
200 µl
Concentration
0.51-0.63 µg/µl in antibody stabilization buffer
Form
FITC-Conjugated
Clonality
Polyclonal
Storage
-20⁰C for long term storage
Application Protocol
Western Blot
1:500
Protein
Uniprot #
Q91ZQ5
Overview
Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester.
Molecular Function
Hydrolase, Isomerase
Subcellular Location
Cytoplasm, Cell membrane; Lipid anchor, Microsome membrane
Expression
Retinal pigment epithelium specific
Structure
Interacts with MYO7A; this mediates light-dependent intracellular transport of RPE65.
Alternative Nomenclature
All-trans-retinyl-palmitate hydrolase antibody
LCA 2 antibody
Leber congenital amaurosis antibody
p63 antibody
rd 12 antibody
Retinal pigment epithelium specific 61 kDa protein antibody
Retinal pigment epithelium specific 65 kDa protein antibody
retinitis pigmentosa 20 antibody
Retinoid isomerohydrolase antibody
RP20 antibody
Protein information supplied by UniProt
Select your currency:
(c) FabGennix International Inc.