General Information
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Product
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AKT1 Antibody BIOTIN-Conjugated
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Description
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BIOTIN-Conjugated RAC-alpha serine/threonine-protein kinase Antibody
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within the last 50 amino acid on human RAC-alpha serine/threonine-protein kinase protein.
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Accession #
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GeneBank: AAA36539
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.58-0.62 µg/µl in antibody stabilization buffer
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Form
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BIOTIN-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Western Blot
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1:500
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Protein
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Uniprot #
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P31749
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Overview
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One of 3 serine/threonine-protein kinases (AKT1-AKT3) regulates many processes including metabolism, proliferation, cell survival, growth and angiogenesis.
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Molecular Function
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Developmental protein; Kinase; Serine/threonine-protein kinase; Transferase
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Subcellular Location
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Cytoplasm; Nucleus; Cell membrane
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Expression
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Expressed in prostate cancer and all human cell types.
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Structure
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Interacts with and phosphorylated by PDPK1. Interacts with several proteins invovled in phosphorylation and ubiquitination
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Alternative Nomenclature
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PKB antibody
Protein Kinase B Alpha antibody
RAC Serine/Threonine Protein Kinase antibody
vAKT Murine Thymoma Viral Oncogene Homolog 1 antibody
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