General Information

Product

C-Myc Antibody

Description

Affinity Purified myc proto-oncogene protein Antibody N-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Cat, Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 200-250 on human cMyc protein.

Accession #

NCBI:  NP_002458

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P01106

Overview

Transcription factor that binds DNA in non-specific manner.  Also specifically recognizes the core sequence 5'CAC[GA]TG-3'.  Activates transcription of growth-related genes.

Molecular Function

Activator; Transcription regulation; DNA-binding

Subcellular Location

Nucleus

Structure

Contains 1 basic helix-loop-helix domain

Alternative Nomenclature

AU016757 antibody

Avian myelocytomatosis viral oncogene homolog antibody

bHLHe39 antibody

c Myc antibody

Cellular myelocytomatosis oncogene antibody

Class E basic helix-loop-helix protein 39 antibody

MRTL antibody

Myc antibody

Myc protein antibody

Myc proto oncogene protein antibody

myc-related translation/localization regulatory factor antibody

MYCC antibody

Myelocytomatosis oncogene antibody

Niard antibody

Nird antibody

Oncogene Myc antibody

Proto-oncogene c-Myc antibody

Protooncogene homologous to myelocytomatosis virus antibody

RNCMYC antibody

Transcription factor p64 antibody

Transcriptional regulator Myc-A antibody

V-Myc avian myelocytomatosis viral oncogene homolog antibody

General Information

Product

C-Myc Antibody Affinity Purified

Description

Affinity Purified myc proto-oncogene protein Antibody C-epitope

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Cat, Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 400-454 on human cMyc protein.

Accession #

NCBI:  NP_002458

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P01106

Overview

Transcription factor that binds DNA in non-specific manner.  Also specifically recognizes the core sequence 5'CAC[GA]TG-3'.  Activates transcription of growth-related genes.

Molecular Function

Activator; Transcription regulation; DNA-binding

Subcellular Location

Nucleus

Structure

Contains 1 basic helix-loop-helix domain

Alternative Nomenclature

AU016757 antibody

Avian myelocytomatosis viral oncogene homolog antibody

bHLHe39 antibody

c Myc antibody

Cellular myelocytomatosis oncogene antibody

Class E basic helix-loop-helix protein 39 antibody

MRTL antibody

Myc antibody

Myc protein antibody

Myc proto oncogene protein antibody

myc-related translation/localization regulatory factor antibody

MYCC antibody

Myelocytomatosis oncogene antibody

Niard antibody

Nird antibody

Oncogene Myc antibody

Proto-oncogene c-Myc antibody

Protooncogene homologous to myelocytomatosis virus antibody

RNCMYC antibody

Transcription factor p64 antibody

Transcriptional regulator Myc-A antibody

V-Myc avian myelocytomatosis viral oncogene homolog antibody

General Information

Product

Phantom Antibody

Description

Affinity Purified Phantom isoform A Antibody N-epitope

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

N-epitope synthetic peptide corresponding to unique amino acid sequences on D. melanogaster Phantom protein.

Accession #

NCBI: NP_573319.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9VWR5

Overview

Plays a role in the metabolism of insect hormones through ecdysteroid C25-hydroxylase activity.  May also funciton in the breakdown of synthetic insecticides.

Molecular Function

Monooxygenase, Oxireductase

Subcellular Location

Endoplasmic reticulum membrane, Peripheral membrane protein, Microsome membrane

Expression

First detected at early blastoderm stage 4, and stripes of expression remain through step 10.  Expression is not detectable during germ band retraction and some expression resumes during stae 15-17.  Low levels of expression are detected in larval brain and fat body.

Alternative Nomenclature

Cytochrome P450 306a1 antibody

Dmphm antibody

Exo antibody

EXO1 antibody

Exocephalon antibody

Protein phantom antibody

General Information

Product

Phantom Antibody

Description

Affinity Purified Phantom isoform A Antibody Mid-Region

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Drosophila melanogaster

Immunogen

Mid region epitope synthetic peptide corresponding to unique amino acid sequences on D. melanogaster Phantom protein.

Accession #

NCBI: NP_573319.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Mid-Region

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9VWR5

Overview

Plays a role in the metabolism of insect hormones through ecdysteroid C25-hydroxylase activity.  May also funciton in the breakdown of synthetic insecticides.

Molecular Function

Monooxygenase, Oxireductase

Subcellular Location

Endoplasmic reticulum membrane, Peripheral membrane protein, Microsome membrane

Expression

First detected at early blastoderm stage 4, and stripes of expression remain through step 10.  Expression is not detectable during germ band retraction and some expression resumes during stae 15-17.  Low levels of expression are detected in larval brain a

Alternative Nomenclature

Cytochrome P450 306a1 antibody

Dmphm antibody

Exo antibody

EXO1 antibody

Exocephalon antibody

Protein phantom antibody

General Information

Product

Phantom Antibody Affinity Purified

Description

Affinity Purified Phantom isoform A Antibody C-epitope

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Drosophila melanogaster

Immunogen

C-epitope synthetic peptide corresponding to unique amino acid sequences on D. melanogaster Phantom protein.

Accession #

NCBI: NP_573319.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9VWR5

Overview

Plays a role in the metabolism of insect hormones through ecdysteroid C25-hydroxylase activity.  May also funciton in the breakdown of synthetic insecticides.

Molecular Function

Monooxygenase, Oxireductase

Subcellular Location

Endoplasmic reticulum membrane, Peripheral membrane protein, Microsome membrane

Expression

First detected at early blastoderm stage 4, and stripes of expression remain through step 10.  Expression is not detectable during germ band retraction and some expression resumes during stae 15-17.  Low levels of expression are detected in larval brain a

Alternative Nomenclature

Cytochrome P450 306a1 antibody

Dmphm antibody

Exo antibody

EXO1 antibody

Exocephalon antibody

Protein phantom antibody

General Information

Product

Punt Antibody

Description

Affinity Purified Punt receptor Serine/Threonine kinase (punt) Antibody

Verified Applications

ELISA, ICC, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Synthetic peptide corresponding to C terminal amino acids 497-515 of Drosophila melanogaster PUNT protein. Peptides were amidated for conjugation.

Sequence:

QLLIKNHTNIDDAKESTNC

Accession #

GenBank: L38495.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q24468

Overview

ATP + [receptor-protein] = ADP + [receptor-protein] phosphate.

Molecular Function

Kinase, Receptor, Serine/threonine-protein kinase, Transferase

Subcellular Location

Activin receptor complex, Plasma membrane

Structure

Contains protein kinase domain.

Alternative Nomenclature

Activin A receptor 88CD antibody
Activin receptor type II antibody
Atr antibody
Atr88CD antibody
AtrII antibody
dlhC antibody
Dorsal holes C antibody
j5A5 antibody
Pun antibody
Put antibody
STKC antibody
TGF beta l antibody
TGF beta type receptor like antibody
Tgf r antibody

General Information

Product

Punt Antibody

Description

Affinity Purified Punt receptor Serine/Threonine kinase (punt) Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

N-epitope synthetic peptide corresponding to unique amino acid sequences on D. melanogaster Punt protein.

Accession #

GenBank: L38495.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q24468

Overview

ATP + [receptor-protein] = ADP + [receptor-protein] phosphate.

Molecular Function

Kinase, Receptor, Serine/threonine-protein kinase, Transferase

Subcellular Location

Activin receptor complex, Plasma membrane

Structure

Contains protein kinase domain.

Alternative Nomenclature

Activin A receptor 88CD antibody
Activin receptor type II antibody
Atr antibody
Atr88CD antibody
AtrII antibody
dlhC antibody
Dorsal holes C antibody
j5A5 antibody
Pun antibody
Put antibody
STKC antibody
TGF beta l antibody
TGF beta type receptor like antibody
Tgf r antibody

General Information

Product

S100 beta Antibody Affinity Purified

Description

Affinity Purified Protein S100-P Antibody N-epitope

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Rat

Immunogen

N-epitope synthetic peptide corresponding to unique amino acid sequences on human S100 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P25815

Overview

May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).

Molecular Function

Calcium-dependent protein binding, calcium ion binding, magnesium ion binding

Subcellular Location

Nucleus, cytoplasm, Cell projection > microvillus membrane

Expression

Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial n

Structure

Homodimer and heterodimer with S100A1. Interacts with S100PBP and S100Z. Interacts with CACYBP in a calcium-dependent manner. Dimeric form binds to and activates EZR/Ezrin by unmasking its F-actin binding sites. Interacts with PPP5C (via TPR repeats); the

Alternative Nomenclature

NEF antibody

S 100 calcium binding protein beta chain antibody

S 100 protein beta chain antibody

S 100 protein beta subunit antibody

S100 calcium-binding protein B antibody

General Information

Product

S100 beta Antibody Affinity Purified

Description

Affinity Purified Protein S100-P Antibody C-epitope

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Rat

Immunogen

C-epitope synthetic peptide corresponding to unique amino acid sequences on human S100 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P25815

Overview

May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).

Molecular Function

Calcium-dependent protein binding, calcium ion binding, magnesium ion binding

Subcellular Location

Nucleus, cytoplasm, Cell projection > microvillus membrane

Expression

Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial n

Structure

Homodimer and heterodimer with S100A1. Interacts with S100PBP and S100Z. Interacts with CACYBP in a calcium-dependent manner. Dimeric form binds to and activates EZR/Ezrin by unmasking its F-actin binding sites. Interacts with PPP5C (via TPR repeats); the

Alternative Nomenclature

NEF antibody

S 100 calcium binding protein beta chain antibody

S 100 protein beta chain antibody

S 100 protein beta subunit antibody

S100 calcium-binding protein B antibody

General Information

Product

S100 beta Antibody

Verified Applications

CM, ELISA, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse

Immunogen

Full length protein of human S100 beta/beta homodimer.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P25815

Overview

May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).

Molecular Function

Calcium-dependent protein binding, calcium ion binding, magnesium ion binding

Subcellular Location

Nucleus, cytoplasm, Cell projection > microvillus membrane

Expression

Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.

Structure

Homodimer and heterodimer with S100A1. Interacts with S100PBP and S100Z. Interacts with CACYBP in a calcium-dependent manner. Dimeric form binds to and activates EZR/Ezrin by unmasking its F-actin binding sites. Interacts with PPP5C (via TPR repeats); the interaction is calcium-dependent and modulates PPP5C activity.

Alternative Nomenclature

NEF antibody

S 100 calcium binding protein beta chain antibody

S 100 protein beta chain antibody

S 100 protein beta subunit antibody

S100 calcium-binding protein B antibody