General Information
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Product
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RPE65 Peptide
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Description
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Antigenic Blocking Peptide RPE65 Antibody
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide corresponding to unique amino acid sequence on mouse RPE65 protein.
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Accession #
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GenBank: AAL01119.1
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q91ZQ5
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Overview
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Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester.
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Molecular Function
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Hydrolase, Isomerase
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Subcellular Location
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Cytoplasm, Cell membrane; Lipid anchor, Microsome membrane
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Expression
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Retinal pigment epithelium specific
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Structure
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Interacts with MYO7A; this mediates light-dependent intracellular transport of RPE65.
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Alternative Nomenclature
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All-trans-retinyl-palmitate hydrolase antibody
LCA 2 antibody
Leber congenital amaurosis antibody
p63 antibody
rd 12 antibody
Retinal pigment epithelium specific 61 kDa protein antibody
Retinal pigment epithelium specific 65 kDa protein antibody
retinitis pigmentosa 20 antibody
Retinoid isomerohydrolase antibody
RP20 antibody
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